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Journals / Türk Dermatoloji Dergisi / 2016 / Cilt: 10 - Sayı: 4

Eozinofilik Dermatozların Sitolojik Bulguları: 88 Hastanın Retrospektif Analizi

Cytologic Findings of Eosinophilic Dermatoses: a Retrospective Analysis of 88 Patients

Murat DURDU
Pages
145–151
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Cytologic examination of people with eosinophilic skin diseases cytologic findings accompanying eosinophils could help for diagnosis of some diseases.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Eosinophilic skin infiltration may develop as a result of a variety of infectious, inflammatory, and neoplastic diseases.
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Key Findings & Data:In this retrospective study, our aim was to define the cytologic findings of eosinophilic dermatoses and to develop an algorithmic approach based on the cytologic findings.Methods: Patients who applied to the dermatology polyclinic through January 2010 to January 2015 could not be diagnosed only by clinical examination were further evaluated with May-Grunwald-Giemsa-stained preparations by a dermatologist.
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Conclusion & Impact:Conclusion: Cytologic examination of people with eosinophilic skin diseases cytologic findings accompanying eosinophils could help for diagnosis of some diseases.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Eosinophilic skin infiltration may develop as a result of a variety of infectious, inflammatory, and neoplastic diseases. To distinguish these diseases histopathologic examination is usually considered. So far, only a few studies have investigated cytologic findings of some eosinophilic diseases. In this retrospective study, our aim was to define the cytologic findings of eosinophilic dermatoses and to develop an algorithmic approach based on the cytologic findings.Methods: Patients who applied to the dermatology polyclinic through January 2010 to January 2015 could not be diagnosed only by clinical examination were further evaluated with May-Grunwald-Giemsa-stained preparations by a dermatologist. Patients with abundant eosinophils in microscopic examination were included in this study. After routine cytologic examination additional staining was also performed in some of these patients. The final diagnosis was established according to their clinical laboratory and histopathologic findings. Results: Over a 5-year period, 88 of 3.214 patients (2.7%) who underwent cytologic examination at our center had plenty of eosinophils. According to the final diagnoses, 44 lesions (50%) were spongiotic dermatitis, 17 lesions (19.3%) were infectious diseases, 13 lesions (14.8%) were autoimmune bullous, 11 lesions (12.5%) were idiopathic eosinophilic diseases, and 3 lesions (3.4%) were granulomatous diseases. Conclusion: Cytologic examination of people with eosinophilic skin diseases cytologic findings accompanying eosinophils could help for diagnosis of some diseases.

Özet

Amaç: Çok sayıda enfeksiyöz, enflamatuvar ve neoplastik hastalık deride eozinofilik infiltrasyona neden olur. Bu hastalıklar arasında ayrım genellikle histopatolojik inceleme ile yapılır. Buna karşın, eozinofilik hastalıkların sitolojik bulgularını inceleyen az sayıda çalışma yapılmıştır. Bu geriye dönük çalışmada, eozinofilik dermatozların sitolojik bulgularını tanımlamak ve sitolojik bulgulara dayalı algoritma geliştirmek amaçlanmıştır. Yöntemler: Ocak 2010 ile Ocak 2015 tarihleri arasında dermatoloji polikliniğine başvuran ve tek başına klinik muayene ile tanı konulamadığı için sitolojik inceleme yapılan hastalarda May-Grünwald-Giemsa boyalı preparatlar tek bir dermatolog tarafından incelendi. Yapılan mikroskobik incelemede bol eozinofil saptanan hastalar çalışmaya dahil edildi. Rutin sitolojik inceleme sonrası bazı hastalarda ek boyamalar yapıldı. Hastaların kesin tanısı klinik, laboratuvar ve histopatolojik bulgulara göre konuldu. Bulgular: Beş yıllık dönemde merkezimizde sitolojik incelemesi yapılan 3,214 hastanın 88'inde (%2,7) bol eozinofili saptandı. Kesin tanı sonrası bu eozinofilik dermatozların 44 (%50)'ü spongiotik dermatit, 17 (%19,3)'si enfeksiyöz hastalık, 13'ü (%14,8) otoimmün büllöz hastalık, 11'i (%12,5) idiyopatik eozinofilik dermatoz ve 3'ü (%3,4) granülomatöz hastalık idi. Sonuç: Eozinofilik dermatozlarda yapılan sitolojik incelemede eozinofillere eşlik eden sitolojik bulguların tespit edilmesi ile birçok hastalığın tanısı konulabilir.

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Cite This Article

DURDU, M. (2022). Eozinofilik Dermatozların Sitolojik Bulguları: 88 Hastanın Retrospektif Analizi. Türk Dermatoloji Dergisi, Cilt: 10 - Sayı: 4, 145–151. https://ajindex.com/articles/621606

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