Journals / Türk Beyin Damar Hastalıkları Dergisi / 1998 / Cilt: 4 - Sayı: 1

Local intraarterial thrombolytic therapy in acute cerebral artery occlusions

Akut serebral arter tıkanmalarında süperselektif lokal intraarteriyel trombolitik tedavi

Pages
99–108
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Finally, it is suggested that local intraarterial fibrinolysis may be an effective treatment in the selected cases of acute cerebrovascular occlusion, though, further detailed studies are necessary for firm conclusions

📌 3 Key Takeaways

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Objective & Hypothesis:In this report, authors present their initial experience with local intraarterial fibrinolytic therapy in acute cerebrovascular occlusion. 9 patients have been treated by local intraarterial fibrinolysis.
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Key Findings & Data:Thrombolysis was angiographically successful in 6 patients, showing complete recanalization.
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Conclusion & Impact:Finally, it is suggested that local intraarterial fibrinolysis may be an effective treatment in the selected cases of acute cerebrovascular occlusion, though, further detailed studies are necessary for firm conclusions
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this report, authors present their initial experience with local intraarterial fibrinolytic therapy in acute cerebrovascular occlusion. 9 patients have been treated by local intraarterial fibrinolysis. Following the placement of the microcatheter into or adjacent to the thrombi, urokinase was infused. Thrombolysis was angiographically successful in 6 patients, showing complete recanalization. One patient died secondary to hemorrhage into the infarcted area. No or minimal neurologic deficits were present in all 6 patients with angiographically demonstrated recanalization. Finally, it is suggested that local intraarterial fibrinolysis may be an effective treatment in the selected cases of acute cerebrovascular occlusion, though, further detailed studies are necessary for firm conclusions

Özet

Bu çalışmada akut serebrovasküler oklüzyonda lokal intraarteriyel fibrinolitik tedavi ile ilgili ön deneyimler sunulmaktadır. 9 olguya ' lokal intraarteriyel fibrinolizis uygulanmıştır. Trombus içine veya komşuluğuna yerleştirilen mikrokateterden ürokinaz verilmiştir. 6 i; olguda tromboliz ile anjiyografik olarak başarılı olunmuş, tam rekanalizasyon sağlanmıştır. Bir hasta tedavi sonrası enfarkt alanına hemoraji ile kaybedilmiştir. Anjiyografik olarak rekanalizasyonun sağlandığı 6 hastanın hiçbirinde nörolojik sekel kalmamış veya ancak minimal bulgu kalmıştır. Kesin bir yargı için ileri çalışmalar gerekli olmakla birlikte, akut serebrovasküler olaylarda,iyi seçilmiş erken başvuran olgularda, lokal intraarteriyel fibrinolizisin etkili bir tedavi yöntemi olabileceği düşünülmektedir.

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Cite This Article

ÇEKİRGE, S. (2022). Local intraarterial thrombolytic therapy in acute cerebral artery occlusions. Türk Beyin Damar Hastalıkları Dergisi, Cilt: 4 - Sayı: 1, 99–108. https://ajindex.com/articles/620379

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