Journals / Tüberküloz ve Toraks / 1999 / Cilt: 47 - Sayı: 4

The relationship between chronic obstructive pulmonary disease and plasma carnitin levels

Kronik obstrüktif akciğer hastalığı ile plazma karnitin düzeyleri arasındaki ilişki

Pages
431–435
Publication Date
2022-11-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, it could be suggested that carnitine, an indicator of the energy metabolism, had no role on the development of respiratory failure in the chronic obstructive pulmonary disease.

📌 3 Key Takeaways

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Objective & Hypothesis:Thirtytiwo male patients with respiratory failure being hospitalized for exacerbation of chronic obstructive pulmonary disease and 22 healthy adult males were included in the present study.
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Key Findings & Data:The ages of the patients varied between 80 and 42 with the average of'61.65 ± 1.30.
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Conclusion & Impact:In conclusion, it could be suggested that carnitine, an indicator of the energy metabolism, had no role on the development of respiratory failure in the chronic obstructive pulmonary disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Thirtytiwo male patients with respiratory failure being hospitalized for exacerbation of chronic obstructive pulmonary disease and 22 healthy adult males were included in the present study. The ages of the patients varied between 80 and 42 with the average of'61.65 ± 1.30. The ages of the control group individuals varied between 86 and 40 with the average of 58.95 ±2.36. There was no significant difference (p> 0.05) between the average ages of the two groups when they were compared statistically. Total free and ester serum carnitine levels and pretreatment arterial blood gases were studied following 8 hours of hangar period. Ho statistical difference (p> 0.05) was observed between groups when the total, free and ester plasma carnitine levels were compared. In conclusion, it could be suggested that carnitine, an indicator of the energy metabolism, had no role on the development of respiratory failure in the chronic obstructive pulmonary disease.

Özet

Bu çalışmaya KOAH egzezarbasyonu nedeniyle hospitalize edilen solunum yetmezlikli 32 erkek hasta ve 22 sağlıklı erkek yetişkin alındı. Hastaların yaş grupları 80 ile 42 arasında değişmekte olup yaş ortalaması 61.65 ± 1.30 idi. Kontrol grubunda ise yaşlar 86 ile 40 arasında değişmekte olup yaş ortalamaları 58.95 ± 2.36 idi. Yaş ortalamaları olarak iki grup arasında istatistiksel olarak anlamlı bir fark yoktu (p> 0.05). Hastalarda ve kontrol grubunda 8 saatlik açlık periyodunu takiben serum total, serbest, ester karnitin düzeyleri ve tedavi öncesi arteriyel kan gazları çalışıldı. Plazma total, serbest ve ester karnitin düzeyleri hasta kontrol grubu ile karşılaştırıldığında aralarında istatistiksel olarak anlamlı bir fark olmadığı görüldü (p> 0.05). Bu çalışma ile enerji metabolizmasının göstergelerinden olan karnitinin KOAH'da solunum yetmezliği gelişmesinde önemli bir rolünün olmadığı sonucuna vardık.

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Cite This Article

YAKIT, C., ÇELİK, V. K., ATALAY, A., SEYFİKLİ, Z., TOPCU, S. (2022). The relationship between chronic obstructive pulmonary disease and plasma carnitin levels. Tüberküloz ve Toraks, Cilt: 47 - Sayı: 4, 431–435. https://ajindex.com/articles/619503

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