AI Summary & Key Takeaways
AI InsightResults were discussed.
📌 3 Key Takeaways
Abstract
Twelve cases of idiopathic pulmonary fibrosis who had been hospitalized in our chest department evaluated for diagnostic and therapeutic management, retrospectively. Mean age was 61.4 ± 14.3 and male/female ratio was equal. Reticular pattern was observed on %41.7 of cases, reticulonodular pattern was observed on %16.6 of cases and honey-combing presented on %41.7 of cases on high-resolution computed tomography. Pulmonary function tests showed reticular pattern. While DLCO was %59.1 ± 32.9 (mean % predictive level), mean P (A-a) O2 was found as 36.2 ± 18.3. Open lung biopsy was used for one patient as a diagnostic approach, transbronchial biopsy was chosen for 5 patients. EBV IgG was found positive on 3 cases, four patients had positive results for CMV IgG, and two patients had positive results for CMV IgM, steroids were the first choise for treatment of %58.4 of the cases. Symptomatic therapy was used for three cases (%25), clinical course wasn't observed on eight of patients (%66.7). Three patients died (%25.6). Results were discussed.
Özet
Kliniğimizde izlenen 12 İPF (İdiopatik Pulmoner Fibrozis) olgusu tanı ve tedavi yaklaşımı açısından retrospektif olarak değerlendirildi. Olguların yaş ortalaması 61.4 ± 14.3 ve erkek/kadın oranı bir idi. Yüksek rezolüsyonlu bilgisayarlı tomografi (YRBT) bulguları; 5 olguda (%41.7) interlobüler septal kalınlaşma; 2 olguda (%16.6) retikülonodüler patern, 5 olguda (%41.7) bal peteği paterni gözlendi. Solunum fonksiyon testlerinde restriktif patern gözlenirken, ortalama DLCO (% beklenen değer) %59.1 ± 32.9, alveolo-arteriyoler gradient ortalama 36.2 ± 18.3 bulundu. Tanı amaçlı bir olguya açık akciğer biyopsisi uygulanırken, 5 olguya TBAB uygulanmıştı. Üç hastada (%25) EBV IqG (+), 4 hastada (%33.3) CMV IgG (+), 2 hastada (%16.6) CMV IgM (+) bulundu. Tedavide steroidler ilk sırada yer alırken (%58.4), semptomatik tedavi (%25) ikinci sıradaydı. Serimizde yer alan 8 hastanın (%66.7) klinik seyrinin izlenemediği, 3 hastanın (%25.6) öldüğü gözlendi. Bulgular literatür bilgileri ile karşılaştırıldı.