Journals / Tüberküloz ve Toraks / 2004 / Cilt: 52 - Sayı: 1

Epidemiological features of bronchial carcinoma cases with environmental asbestos exposure

Çevresel asbest teması olan bronş kanserli olguların epidemiyolojik özellikleri

Pages
5–13
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The epidemiological and clinical features of adenocancer cases exposed to asbestos environmentally were not different than those of adenocancer cases exposed to asbestos occupationally.

📌 3 Key Takeaways

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Objective & Hypothesis:Due to environmental asbestos exposure, asbestos related lung diseases are common in Eskişehir district of Anatolia.
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Key Findings & Data:From May 1997 to December 2000, 301 cases were included in the study.
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Conclusion & Impact:The epidemiological and clinical features of adenocancer cases exposed to asbestos environmentally were not different than those of adenocancer cases exposed to asbestos occupationally.
🔬Design:Research Article
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters

Abstract

Due to environmental asbestos exposure, asbestos related lung diseases are common in Eskişehir district of Anatolia. In this study we aimed both to determine the epldemiological findings of the patients diagnosed as bronchial carcinoma and to discus the features, which were probably related to asbestos exposure, presented by the patients. From May 1997 to December 2000, 301 cases were included in the study. Of the patients, 97 (32.2%) had epidermoid cell type, 84 (27.9%) had small cell, 39 (13%) had adenocarcinoma, 4 (1.3%) had large cell. Adenocarcinomas were more frequent in women. There were not significant differences among the cell types from the point of mew of the age distributions. Adenocarcinomas were more frequently located in lower lobes of the lungs (36.9%) and more frequently showed peripheral locations (45.9%) than other cell types (20.6% for epidermoid and 14.6% for small cell). Pleural effusion was more detected in adenocarcinomas (48.7% to 17.3% in epidermoid, 18.3% in small cell). The duration of smoking was shortest in adenocarcinomas, mean 32.4 years; the same duration was 56.2 years for epidermoid carcinomas. Of the patients, 54% had asbestos exposure. Adenocarcinomas were more frequently detected in the patients who exposed to asbestos but did not smoke. Our findings support that asbestos exposure may increase adenocancer frequency. The epidemiological and clinical features of adenocancer cases exposed to asbestos environmentally were not different than those of adenocancer cases exposed to asbestos occupationally.

Özet

Asbest teması ile bağlantılı akciğer hastalıkları Eskişehir çevresinde oldukça yaygındır. Bu çalışmamızda, bronş kanserli hastaların epidemiyolojik bulgularının tanımlanarak, saptanacak özelliklerin tümör hücre tipi, yerleşimi ve etyolojik ilişkileri ile irdelenmesi amaçlandı. Çalışmaya, 1997-2000 yılları arasında izlenen, histopatolojik olarak akciğer kanseri tanısı almış 301 (277'si erkek, 24'ü kadın) olgu alındı. Olguların 97 (%32.2)'si epidermoid kanser, 84 (%27.9)'ü küçük hücreli kanser, 39 (%13)'u adenokanser, 4 (%1.3)'ü büyük hücreli kanser idi. Adenokanser diğer hücre tiplerine göre kadınlarda daha sıktı. Yaş dağılımı olarak histopatolojik tipler arasında istatistiksel olarak anlamlı fark izlenmedi. Adenokanser yerleşimi akciğerin alt loblarında (%36.9) oe periferde (%45.9) daha sıktı. Epidermoid kanser %20.6 ve küçük hücreli kanser % 14.6 oranında periferde yerleşikti. Pleural sıvı adenokanserlilerde daha fazla saptandı (%48.7), epidermoid kanserde %17.3 ue küçük hücreli kanserde %18.3 oranında plevral sıvı eşlik ediyordu. Sigara kullanma süresi adenokanserde ortalama 32.4 yıl, epidermoid kanserde 56.2 yıl idi. Hastaların %54'ünde asbest teması vardı. Adenokanser, sigara içmeyen ve asbest te-ması olan hastalarda daha sık izlendi. Bulgularımız asbest temasının kendi başına adenokanser riskini arttırabileceği kanaatini verdi. Adenokanserü olguların epidemiyolojik ve klinik bulguları ve çevresel asbest temas ilişkileri mesleksel asbest temaslı serilerin özellikleri ile uyumlu idi.

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Cite This Article

ÇELİK, H., METİNTAŞ, S., METİNTAŞ, M., ERGİNEL, S., UÇGUN, İ., ALATAŞ, F., BEKTAŞ, Y., GÜRBÜZ, B., HARMANCI, E. (2022). Epidemiological features of bronchial carcinoma cases with environmental asbestos exposure. Tüberküloz ve Toraks, Cilt: 52 - Sayı: 1, 5–13. https://ajindex.com/articles/619271

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