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Journals / Tüberküloz ve Toraks / 2008 / Cilt: 56 - Sayı: 4

Akut venöz tromboemboli tedavisinde streptokinaz kullanımına bağlı akut anürik böbrek yetmezliği olgusu ve streptokinazın renal yan etkilerinin gözden geçirilmesi

Acute anuric renal failure with streptokinase therapy in a patient with acute venous thromboembolic disease and the review of renal side effects of streptokinase

Zeynep ÖNEN
Eriş Banu GÜLBAY
Gülseren KARABIYIKOĞLU
Akkoca Öznur YILDIZ
Pages
456–461
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After therapy patient developed acute anuric renal failure without an evidence of bleeding or immunologic reaction and we would like to review the renal side effects of streptokinase in patients with venous thromboembolic disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The benefits of thrombolytic therapy in acute myocardial infarction are now well established.
📊
Key Findings & Data:However many uncertainties, such as adverse effects, are still remain in venous thromboembolic disease.
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Conclusion & Impact:After therapy patient developed acute anuric renal failure without an evidence of bleeding or immunologic reaction and we would like to review the renal side effects of streptokinase in patients with venous thromboembolic disease.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The benefits of thrombolytic therapy in acute myocardial infarction are now well established. However many uncertainties, such as adverse effects, are still remain in venous thromboembolic disease. We describe a unique patient who treated with streptokinase for the methylen tetrahydrofolate reductase mutation associated acute deep vein thrombosis and massive pulmonary embolism. After therapy patient developed acute anuric renal failure without an evidence of bleeding or immunologic reaction and we would like to review the renal side effects of streptokinase in patients with venous thromboembolic disease.

Özet

Akut miyokard enfarktüsünde, trombolitik tedavide, kullanılan streptokinazın etkileri oldukça iyi bilinmektedir. Oysa streptokinazın venöz tromboembolik hastalık (VTEH) da kullanımı ile ilgili, özellikle de yan etkileriyle ilgili birçok belirsizlik bulunmaktadır. Biz metilen tetrahidrofolat redüktaz mutasyonuna ikincil derin ven trombozu ve masif pulmoner emboli gelişen bir olguda streptokinaz kullanımına bağlı, kanama olmadan veya immünolojik özellik göstermeyen akut böbrek yetmezliği tablosunu ve VTEH da renal yan etkileri değerlendirmek istiyoruz.

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Cite This Article

ÖNEN, Z., GÜLBAY, E. B., KARABIYIKOĞLU, G., YILDIZ, A. Ö. (2022). Akut venöz tromboemboli tedavisinde streptokinaz kullanımına bağlı akut anürik böbrek yetmezliği olgusu ve streptokinazın renal yan etkilerinin gözden geçirilmesi. Tüberküloz ve Toraks, Cilt: 56 - Sayı: 4, 456–461. https://ajindex.com/articles/619005

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References (16)

  1. McGrath KG, Zeffren B, Alexander J, et al. Allergic reaktions to streptokinase consistant with anaphylactic or antigen-antibody complex mediated damage. J Allergy Clin Immunol 1985; 76: 453-7
  2. Schulman S. Unresolved issues in anticoagulant therapy. J Thromb Haemost 2003; 1: 1464-70
  3. Fennerty A, Levine M, Hirsh J. Hemorrhagic complications of thrombolytic therapy in the treatment of myocardial infarction and venous thromboembolism. Chest 1989; 95: 88-97
  4. Califf R, Fortin D, Tenaglia A, Sane D. Clinical risks of thrombolytic therapy. Am J Cardiol 1992; 69: 12-20
  5. McGrath K, Patterson R. Immunology of streptokinase in human subjects. Clin Exp Immunol 1985; 62: 421-6
  6. Birnbaum Y, Hasdai D, Stahl B. Renal adverse effects of streptokinase therapy. Int J Cardiol 1994; 46: 1-6
  7. Toupin LR, Blanchard DG. Acute anuric renal failure: A complication of combined thrombolytic and thrombotic therapy. Int J Cardiol 1993; 40: 283-85
  8. Spangen L, Lilijeqvist L, Ljungdahl I, Somell A. Temporary changes in the renal function following streptokinase therapy. Acta Med Scand 1976; 199: 335-6
  9. Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: Clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet 1999; 353: 1386-9
  10. Meissner AJ, Msiak A, Ziemski JM, et al. Hazards of thrombolytic therapy in deep vein thrombosis. Br J Surg 1987; 74: 991-3
  11. Zahger D, Weiss T, Anner H, Waksman R. Systemic embolization following thrombolytic therapy for acute myocardial infarction. Chest 1990; 97: 754-6
  12. Lessman RK, Johnson SF, Coburn JW, Kaufman JJ. Renal artery embolism–Clinical features and long-term follow-up of 17 cases. Ann Intern Med 1978; 89: 477-82
  13. Riedker P, Michel T. Streptokinase therapy and cholesterol embolization. Am J Cardiol 1989; 87: 357-8
  14. Rosman H, Davis T, Reddy D, Goldstein S. Cholesterol embolization: Clinical findings and implications. J Am Coll Cardiol 1990; 15: 1296-9
  15. Dykiewicz MS, McGrath KG, Davison R, et al. Identification of patients at risk of anaphylaxis due to streptokinase. Arch Intern Med 1986; 146: 305-9
  16. Marbert GA, Eichlisberger R, Duchert F. Side effects of thrombolytic treatment with porcin plasmin and low dose streptokinase. Thromb Haemost 1982; 48: 196-200.