Journals / Tüberküloz ve Toraks / 2008 / Cilt: 56 - Sayı: 1

Akut solunum yetmezlikli KOAH olgularında ventilatörden ayırma sürecinin değerlendirilmesi

Evaluation of the weaning process in COPD patients with acute respiratory failure

Pages
64–73
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, whether the WD in COPD patients is less or greater than 24 hours is not only determined by the medical treatment administered, but also by the patient and disease characteristics.

📌 3 Key Takeaways

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Objective & Hypothesis:Based on our observations in chronic obstructive pulmonary disease (COPD) patients admitted to our respiratory intensive care unit due to acute respiratory failure suggesting a significant variation in weaning duration (WD), we conducted a retrospective cohort study in such patients.
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Key Findings & Data:Group 1: patients with a WD ≤ 24 hours (n= 32), Group 2: patients with a WD > 24 hours (n= 27).
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Conclusion & Impact:In conclusion, whether the WD in COPD patients is less or greater than 24 hours is not only determined by the medical treatment administered, but also by the patient and disease characteristics.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Based on our observations in chronic obstructive pulmonary disease (COPD) patients admitted to our respiratory intensive care unit due to acute respiratory failure suggesting a significant variation in weaning duration (WD), we conducted a retrospective cohort study in such patients. Fifty-nine patients successfully extubated following invasive mechanical ventilation were included. Syncronized intermittent mandatory ventilation plus pressure support ventilation was used as the weaning mode in mostly. Study population was divided into two groups. Group 1: patients with a WD ≤ 24 hours (n= 32), Group 2: patients with a WD > 24 hours (n= 27). Groups were compared with respect to demographics, vital signs, arterial blood gases, laboratory values, and the treatment characteristics. The average WD was 13 ± 8 and 58 ± 34 hours in group 1 and group 2, respectively (p 24 hours: elevated baseline heart rate, alkaline pH at the day of weaning, duration of midazolam infusion, and emphysematous findings on chest X-ray. In conclusion, whether the WD in COPD patients is less or greater than 24 hours is not only determined by the medical treatment administered, but also by the patient and disease characteristics.

Özet

Akut solunum yetmezliği nedeniyle solunumsal yoğun bakım ünitesine kabul edilen kronik obstrüktif akciğer hastalığı (KOAH) olan olgularda invaziv mekanik ventilasyondan ayırma süresinin (AS) belirgin farklılıklar gösterdiği gözleminden hareketle retrospektif kohort çalışma planladık. Çalışmaya invaziv mekanik ventilasyon sonrası başarıyla ekstübe edilen 59 KOAH olgusu alındı. Ayırma modu olarak hastaların çoğunda SIMV + PSV kullanıldı. Çalışma popülasyonu AS’ye göre iki gruba ayrıldı: Grup 1: AS ≤ 24 saat (n= 32), grup 2: AS > 24 saat (n= 27). Gruplar demografik ve klinik özellikleri, vital bulguları, arter kan gazları, laboratuvar bulguları ve tedavi özellikleri açısından karşılaştırıldı. Ortalama AS grup 1’de 13 ± 8 saat, grup 2’de 58 ± 34 saat bulundu (p< 0.001). Lojistik regresyon analizinde AS’nin 24 saatten uzun olması için prediktif faktörler: Bazal kalp hızının yüksek olması, ayırma gününde pH’nın alkalotik olması, midazolam infüzyon süresi ve akciğer grafisinde amfizematöz bulguların baskın olması. Sonuç olarak, KOAH’ta mekanik ventilatörden ayırma süresinin hasta ve hastalığa ait özelliklerin yanı sıra tedavi özelliklerinden de etkilenebileceği kanısındayız.

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Cite This Article

ADIGÜZEL, N., GÜNGÖR, G., KARAKURT, Z., BÖLÜKBAŞI, Y., YARKIN, T., ALTINÖZ, H., MOÇİN, Y. Ö. (2022). Akut solunum yetmezlikli KOAH olgularında ventilatörden ayırma sürecinin değerlendirilmesi. Tüberküloz ve Toraks, Cilt: 56 - Sayı: 1, 64–73. https://ajindex.com/articles/618954

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