Journals / Tüberküloz ve Toraks / 2012 / Cilt: 60 - Sayı: 2

Salbutamol in asthma treatment: With nebulizer or inhaler?

Astım tedavisinde salbutamol; Nebülizerle mi inhalerle mi?

Pages
193–198
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, asthma exacerbation can be treated with pMDIs used through hol-ding chambers in emergency room successfully when applied with dosing scheme appropriate for the patient s age,weight and severity of exacerbation (usually 1/4th of nebule dosing) on the contrary to ordinary method of nebulizers.

📌 3 Key Takeaways

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Objective & Hypothesis:Breath relieving and protective drugs in asthma treatment are applied through pressurized metered dose inhaler(pMDI), nebulizer or dry powder inhaler.
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Key Findings & Data:The short acting beta-2 agonist salbutamol used in acute asthma exacerbation is found in the forms of nebule or pMDI in Turkey.
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Conclusion & Impact:As a result, asthma exacerbation can be treated with pMDIs used through hol-ding chambers in emergency room successfully when applied with dosing scheme appropriate for the patient s age,weight and severity of exacerbation (usually 1/4th of nebule dosing) on the contrary to ordinary method of nebulizers.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Breath relieving and protective drugs in asthma treatment are applied through pressurized metered dose inhaler(pMDI), nebulizer or dry powder inhaler. The short acting beta-2 agonist salbutamol used in acute asthma exacerbation is found in the forms of nebule or pMDI in Turkey. Nebule form is used more frequently in emergency services. The aim of this review is to compare these two routes of administration through clinical efficacy, the amount of drug reac-hing to the lungs and adverse events comprehensively by way of looking through the studies. Additionally effect ofdifferent inhalation techniques through chambers, different methods used in cleaning of them and different types of nebulizers, to the efficacy are investigated. As a result, asthma exacerbation can be treated with pMDIs used through hol-ding chambers in emergency room successfully when applied with dosing scheme appropriate for the patient s age,weight and severity of exacerbation (usually 1/4th of nebule dosing) on the contrary to ordinary method of nebulizers.

Özet

Astım tedavisinde nefes açıcı ya da koruyucu ilaçlar, basınçlı ölçülü doz inhaler (bÖDİ), nebülizer ya da kuru toz inhalerile uygulanmaktadır. Atak tedavisinde kullanılan salbutamolün nebül ve bÖDİ formu bulunmaktadır. Genellikle aracı tüplebirlikte kullanılan bÖDİ ve nebülizer çocuklarda tüm yaş gruplarında kullanılabilir. Türkiyede acil servislere başvuran hastalarda ön planda nebül formu kullanılmaktadır. Bu derlemenin amacı, literatürü incelemek yoluyla acil tedavide kullanımı oldukça yaygın olan nebül ile ölçülü doz inhaleri klinik etkinlik, akciğerde depolanma miktarı ve yan etkiler yönündenkarşılaştırmaktır. Derlemede ayrıca farklı inhalasyon yöntemleri ve bakım yöntemlerinin bÖDİ etkinliğini değiştirebileceği,farklı yöntemlerle çalışan nebülizerlerin de klinik etkinliğinin birbirinden farklı olabileceği ortaya konmuştur. Sonuç olarakacil servise atak nedeniyle başvuran hastalarda alışılagelenin aksine uygun bakım yapılmış aracı tüp yoluyla bÖDİ kullanma becerisine sahip hastalarda, hastanın yaşına, kilosuna ve atak şiddetine göre uygun dozda salbutamol kullanıldığında bÖDİ/aracı tüp kombinasyonunun (yapılan çalışmalara göre nebüle dozunun 1/4ü olacak şekilde) daha kısa sürede iyileşme sağlayarak nebülizere iyi bir alternatif olabileceği düşünülmektedir.

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Cite This Article

CAVKAYTAR, Ö., ŞEKEREL, B. E. (2022). Salbutamol in asthma treatment: With nebulizer or inhaler?. Tüberküloz ve Toraks, Cilt: 60 - Sayı: 2, 193–198. https://ajindex.com/articles/618694

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