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Journals / Tüberküloz ve Toraks / 2013 / Cilt: 61 - Sayı: 1

MicroRNAs and lung cancer

MikroRNA’lar ve akciğer kanseri

Ayşe Gül ZAMANİ
Adil ZAMANİ
Pages
57–62
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review summarizes the current knowledge of miRNAs and their roles in lung cancer.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:MicroRNAs (miRNAs) are a class of non-coding RNAs that hybridize to mRNAs and induce either translation repression or mRNA cleavage.
📊
Key Findings & Data:Patterns of altered miRNA expression in cancer may work as molecular biomarkers for tumor diagnosis, prognosis of disease-specific outcomes, and prediction of therapeutic responses.
💡
Conclusion & Impact:This review summarizes the current knowledge of miRNAs and their roles in lung cancer.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

MicroRNAs (miRNAs) are a class of non-coding RNAs that hybridize to mRNAs and induce either translation repression or mRNA cleavage. Patterns of altered miRNA expression in cancer may work as molecular biomarkers for tumor diagnosis, prognosis of disease-specific outcomes, and prediction of therapeutic responses. In addition, miRNAs can serve as specific targets for gene therapies. This review summarizes the current knowledge of miRNAs and their roles in lung cancer.

Özet

MikroRNA’lar, mRNA’larla hibridize olarak translasyon inhibisyonu ya da mRNA yıkılımına yol açan kodlama yapmayan RNA’lardır. Kanserde değişen miRNA ekspresyonu tümör tanısında, hastalığa özgü prognozun ve tedaviye yanıtın moleküler biyomarkırları olarak kullanılabilir. Ayrıca, miRNA’lar gen tedavisinde özgül hedefler olarak seçilebilir. Bu der- lemede, miRNA’ların akciğer kanserindeki rolü ve yeni gelişmeler özetlenecektir.

🔖

Cite This Article

ZAMANİ, A. G., ZAMANİ, A. (2022). MicroRNAs and lung cancer. Tüberküloz ve Toraks, Cilt: 61 - Sayı: 1, 57–62. https://ajindex.com/articles/618643

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