Journals / Tüberküloz ve Toraks / 2018 / Cilt: 66 - Sayı: 4

Sleep disturbances in patients with lung cancer in Turkey

Türkiye’de akciğer kanseri hastalarında uyku bozuklukları

Pages
297–303
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Multivariate logistic regression analysis showed that patients with moderate to severe pain and dyspnea and severe anxietyhad 2-3 times higher rates of insomnia.Conclusion: In conclusion, our results showed a clear association between sleep disturbances and cancer symptoms.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Sleep quality is known to be associated with the distressing symptoms of cancer.
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Key Findings & Data:The purpose of this study was toanalyze the impact of cancer symptoms on insomnia and the prevalence of sleep-related problems reported by the patients with lungcancer in Turkey.Materials and Methods: Assesment of Palliative Care in Lung Cancer in Turkey (ASPECT) study, a prospective multicenter studyconducted in Turkey with the participation of 26 centers and included all patients with lung cancer, was re-evaluated in terms of sleepproblems, insomnia and possible association with the cancer symptoms.
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Conclusion & Impact:Multivariate logistic regression analysis showed that patients with moderate to severe pain and dyspnea and severe anxietyhad 2-3 times higher rates of insomnia.Conclusion: In conclusion, our results showed a clear association between sleep disturbances and cancer symptoms.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Sleep quality is known to be associated with the distressing symptoms of cancer. The purpose of this study was toanalyze the impact of cancer symptoms on insomnia and the prevalence of sleep-related problems reported by the patients with lungcancer in Turkey.Materials and Methods: Assesment of Palliative Care in Lung Cancer in Turkey (ASPECT) study, a prospective multicenter studyconducted in Turkey with the participation of 26 centers and included all patients with lung cancer, was re-evaluated in terms of sleepproblems, insomnia and possible association with the cancer symptoms. Demographic characteristics of patients and informationabout disease were recorded for each patient by physicians via face-to-face interviews, and using hospital records. Patients who havedifficulty initiating or maintaining sleep (DIMS) is associated with daytime sleepiness/fatigue were diagnosed as having insomnia.Daytime sleepiness, fatigue and lung cancer symptoms were recorded and graded using the Edmonton Symptom Assessment Scale.Results: Among 1245 cases, 48.4% reported DIMS, 60.8% reported daytime sleepiness and 82.1% reported fatigue. The prevalenceof insomnia was 44.7%. Female gender, patients with stage 3-4 disease, patients with metastases, with comorbidities, and with weightloss > 5 kg had higher rates of insomnia. Also, patients with insomnia had significantly higher rates of pain, nausea, dyspnea, andanxiety. Multivariate logistic regression analysis showed that patients with moderate to severe pain and dyspnea and severe anxietyhad 2-3 times higher rates of insomnia.Conclusion: In conclusion, our results showed a clear association between sleep disturbances and cancer symptoms. Because of that,adequate symptom control is essential to maintain sleep quality in patients with lung cancer.

Özet

Giriş: Uyku kalitesinin, kanser semptomlarının şiddetiyle ilişkili olduğu bilinmektedir. Bu çalışmada, Türkiye’de akciğer kanseri hastalarında uyku ile ilişkili sorunların prevalansı ve kanser semptomlarının insomnia üzerine etkisinin araştırılması amaçlandı. Materyal ve Metod: Türkiye’de 26 merkezin katılımıyla gerçekleştirilen, akciğer kanserli olguların dahil edildiği çok merkezli bir çalışma olan ASPECT çalışması verileri, bu hastalarda görülen uyku sorunları, insomni ve bunların kanser semptomları ile ilişkisi yönüyle yeniden değerlendirildi. Hastaların demografik özellikleri ve hastalıkları hakkında bilgi, hasta ile yüz yüze görüşülerek ve hastane kayıtları aracılığıyla derlendi. Uykuyu başlatma ve sürdürme zorluğu (DIMS) ile gündüz artmış uyku hali veya yorgunluk tanımlayan olgular insomni olarak değerlendirildi. Gündüz uyku hali, yorgunluk ve akciğer kanseri semptomları Edmonton Semptom Değerlendirme Skalası kullanılarak kaydedildi. Bulgular: Katılan 1245 olgunun, %48.4’ünde DIMS, %60.8’inde gündüz uyku hali ve %82.1’inde yorgunluk mevcuttu. Insomni prevalansı %44.7 olarak bulundu. Kadın cinsiyet, evre 3-4 hastalık, metastatik hastalık, komorbid hastalıklar ve kilo kaybı > 5 kg olan olgularda insomnia oranı anlamlı olarak daha yüksekti. Diğer yandan insomnisi olan hastalarda ağrı, bulantı, dispne ve anksiyete semptomları anlamlı düzeyde yüksek bulundu. Multivariate lojistik regresyon analizi, orta ileri şiddetli ağrısı ve dispnesi olan, ayrıca ciddi anksiyetesi olan hastalarda insomni sıklığının 2-3 kat fazla olduğunu ortaya koydu. Sonuç: Çalışmamız, kanser semptomları ile uyku kalitesi arasında yakın bir ilişki olduğunu ortaya koymuştur. Bu nedenle, akciğer kanserli hastalarda kaliteli bir uyku için, kanser semptomların yeterince kontrol edilmesi gereklidir.

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Cite This Article

YILMAZ, U., TEKE, T., ACAT, M., BAŞYİĞİT, İ., ÖZÇELİK, M., GÜNBATAR, H., ERBAYCU, A. E., KILIÇ, T., ERDOĞAN, Y., İNTEPE, Y. S., BARIŞ, S. A., BÜLBÜL, Y., ARINÇ, S., BERK, S., ASKER, S., BEŞİROĞLU, M., EROL, S., DALLI, A., SAĞLAM, L., BAHADIR, A. (2022). Sleep disturbances in patients with lung cancer in Turkey. Tüberküloz ve Toraks, Cilt: 66 - Sayı: 4, 297–303. https://ajindex.com/articles/618476

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