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Journals / Turkish Neurosurgery / 2017 / Cilt: 27 - Sayı: 2

Unilateral Subthalamic Nucleus Stimulation in the Treatment of Asymmetric Parkinson's Disease with Early Motor Complications

Michal SOBSTYL
Miroslaw ZABEK
Artur ZACZYNSKI
Wojciech GORECKI
Zbigniew MOSSAKOWSKI
Gra?yna BRZUSZKIEWICZ-KUZMICKA
Pages
294–300
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

COnCLuSIOn: Unilateral STN stimulation is a safe and effective procedure for selected patients with marked asymmetry Parkinson's disease motor symptoms and early motor complications.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: The aim of this study was to assess the results of unilateral subthalamic nucleus (STN) stimulation for the treatment of Parkinson's disease (PD) with marked asymmetry of parkinsonian motor symptoms and early motor complications.
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Key Findings & Data:MATERIAL and METhODS: The clinical series consisted of 32 consecutive PD patients, in whom unilateral STN stimulation was performed.
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Conclusion & Impact:COnCLuSIOn: Unilateral STN stimulation is a safe and effective procedure for selected patients with marked asymmetry Parkinson's disease motor symptoms and early motor complications.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: The aim of this study was to assess the results of unilateral subthalamic nucleus (STN) stimulation for the treatment of Parkinson's disease (PD) with marked asymmetry of parkinsonian motor symptoms and early motor complications. MATERIAL and METhODS: The clinical series consisted of 32 consecutive PD patients, in whom unilateral STN stimulation was performed. All patients were assessed according to the Unified Parkinson's Disease Rating Scale (UPDRS), and Hoehn and Yahr staging. The patients were assessed preoperatively, and at 12, and 24 months after unilateral STN stimulation. 22 patients were followed for 2 years. RESuLTS: Medication off/stimulation on total UPDRS motor scores were improved by 29% when compared to the baseline medication off motor scores. The contralateral motor scores improved by 49%, whereas the axial motor scores by 18% in medication off/stimulation on condition. The duration and severity of levodopa induced dyskinesia were reduced respectively by 73% and by 77%. The daily levodopa dose was decreased by only 10%. COnCLuSIOn: Unilateral STN stimulation is a safe and effective procedure for selected patients with marked asymmetry Parkinson's disease motor symptoms and early motor complications.

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Cite This Article

SOBSTYL, M., ZABEK, M., ZACZYNSKI, A., GORECKI, W., MOSSAKOWSKI, Z., BRZUSZKIEWICZ-KUZMICKA, G. (2022). Unilateral Subthalamic Nucleus Stimulation in the Treatment of Asymmetric Parkinson's Disease with Early Motor Complications. Turkish Neurosurgery, Cilt: 27 - Sayı: 2, 294–300. https://ajindex.com/articles/616987

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References (1)

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