Journals / Turkish Neurosurgery / 2015 / Cilt: 25 - Sayı: 5

Vena Cava Filters are not Superior to Low Molecular Weight Heparin in Venous Thromboembolism Prophylaxis: A Study on Long-term Immobilized neurosurgical Patients

Vena Kava Filtreleri Venöz Tromboembolizm Profilaksisinde Düşük Molekül Ağırlıklı Heparine Üstün Değildir: Uzun Süre Mobilize Olmayan Nöroşirürji Hastaları Üzerinde Yapılan Bir Çalışma

Pages
695–700
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Nevertheless, it is reasonable to prevent PE in patients with proven DVT who have no contraindication for anticoagulant drugs.

📌 3 Key Takeaways

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Objective & Hypothesis:AIm: Deep venous thrombosis (DVT) and pulmonary embolism (PE) are the most frequent surgical problems and associated with high morbidity and mortality.
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Key Findings & Data:Neurosurgical patients constitute a unique group where prophylaxis with anticoagulant and antiaggregant agents are relatively contraindicated due to the natural course of vascular problems such as aneurysms, hemorrhagic tumors or hematomas or increased vulnerability to complex spinal surgeries and trauma. mAterIAl and methOds: We included 67 patients predicted to be immobilized for 2 or more months in this retrospective analysis.
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Conclusion & Impact:Nevertheless, it is reasonable to prevent PE in patients with proven DVT who have no contraindication for anticoagulant drugs.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIm: Deep venous thrombosis (DVT) and pulmonary embolism (PE) are the most frequent surgical problems and associated with high morbidity and mortality. Neurosurgical patients constitute a unique group where prophylaxis with anticoagulant and antiaggregant agents are relatively contraindicated due to the natural course of vascular problems such as aneurysms, hemorrhagic tumors or hematomas or increased vulnerability to complex spinal surgeries and trauma. mAterIAl and methOds: We included 67 patients predicted to be immobilized for 2 or more months in this retrospective analysis. A vena cava filter was inserted between the first and seventh postoperative day in 40 patients in a prophylactic manner whereas 27 patients received low dose heparin for the same purpose. The patients were evaluated for symptomatic DVT or PE. results: Percutaneous insertion was performed for all filters without any complication. DVT occurred in two patients of the filter group and 1 patient of the heparin group. There was no PE recorded in any patient of either group. Patients were followed up for 22 months in the filter and 16 months in the heparin group. COnClusIOn: We conclude that prophylactic filter use in high risk neurosurgical patients is not beneficial and not superior to low-molecularweight heparin use. Nevertheless, it is reasonable to prevent PE in patients with proven DVT who have no contraindication for anticoagulant drugs.

Özet

AmAÇ: Derin ven trombozu ve pulmoner embolizm yüksek morbidite ve mortaliteyle seyreden en sık cerrahi problemler arasında yer alır. Anevrizma gibi vasküler problemler, hemorajik tümörler, hematom, kompleks spinal cerrahi ve travma gibi nöroşirürjiye ait hastalıklar antiagregan ve antikoagülan tedavinin göreceli olarak kontrendike olduğu özel bir grubu oluşturmaktadır.yÖntem ve GereÇler: Bu retrospektif çalışmada, 2 ay veya daha uzun süre immobilize olması beklenen 67 hastanın analizi yapılmıştır. Vena kava filtreleri 40 hastada postoperatif bir ile yedinci günde proflaktik amaçla yerleştirildi. 27 hastada ise aynı amaçla düşük moleküler ağırlıklı heparin kullanıldı. Hastalar yattıkları süreçte ve izlemde semptomatik derin ven trombozu (DVT) ve pulmoner emboli (PE) açısından takip edildi. BulGulAr: Bütün filtreler perkütan yolla yerleştirildi ve işleme ait herhangi bir komplikasyon gelişmedi. Filtre grubunda 2, heparin grubunda 1 hastada DVT gelişti. Her iki grupta PE saptanmadı. Hastalar filtre grubunda ortalama 22 ay, heparin grubunda 16 ay süreyle takip edildi.sOnuÇ: Yüksek riskli nöroşirürji hastalarında prolaktik filtre kullanımının düşük moleküler ağırlıklı heparin kullanımına üstün olmadığı düşünüldü. Buna rağmen DVT'si kanıtlanmış ve antikoagülan ilaçların kontrendike olduğu durumlarda PE'yi önlemede etkin olduğu açıktır.

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Cite This Article

DAGLIOGLU, E., ALAGOZ, F., AKMANGIT, I., DEDE, D., EKICI, I., UYANIK, S. A., AHLAT, B., BELEN, A. D. (2022). Vena Cava Filters are not Superior to Low Molecular Weight Heparin in Venous Thromboembolism Prophylaxis: A Study on Long-term Immobilized neurosurgical Patients. Turkish Neurosurgery, Cilt: 25 - Sayı: 5, 695–700. https://ajindex.com/articles/616973

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References (1)

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