Journals / Turkish Neurosurgery / 2015 / Cilt: 25 - Sayı: 4

effects of Intensive Blood Pressure Lowering on Intracerebral Hemorrhage Outcomes: A Meta-Analysis of Randomized Controlled Trials

Yoğun Kan Basıncı Azaltmanın İntraserebral Kanama Sonuçlarına Etkileri: Randomize Kontrollü Çalışmaların Bir Meta-Analizi

Pages
544–551
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

ResuLTs: Five eligible studies were included and analyzed, involving 3243 patients to use systolic BP (SBP)

📌 3 Key Takeaways

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Objective & Hypothesis:AIm: Elevation of blood pressure (BP) is common after intracerebral hemorrhage (ICH).
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Key Findings & Data:Meta-analysis was performed in terms of the odds ratio (OR) and 95% confidence interval (CI).
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Conclusion & Impact:ResuLTs: Five eligible studies were included and analyzed, involving 3243 patients to use systolic BP (SBP)
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIm: Elevation of blood pressure (BP) is common after intracerebral hemorrhage (ICH). Early BP treatment may be beneficial after ICH, but the effect of intensive BP lowering on ICH outcomes is not known and no systematic review or meta-analysis was published regarding this issue.mATeRIAL and meTHods: We conducted a meta-analysis to compare the effect of more versus less intensive BP targets on clinical outcomes in patients with ICH. Mortality, unfavorable outcome and adverse events were analyzed. Meta-analysis was performed in terms of the odds ratio (OR) and 95% confidence interval (CI). ResuLTs: Five eligible studies were included and analyzed, involving 3243 patients to use systolic BP (SBP)

Özet

AmAÇ: İntraserebral kanama (İSK) sonrasında kan basıncında (KB) artışa sık rastlanır. İSK sonrasında erken KB tedavisi faydalıdır ama yoğun KB azaltmanın İSK sonuçları üzerine etkisi bilinmemektedir ve bu konuyla ilgili herhangi bir yayınlanmış sistematik derleme veya meta-analiz yoktur.yÖNTem ve GeReÇLeR: İSK hastalarında klinik sonuçlar üzerine daha yüksek ve daha düşük KB hedeflerinin etkisini karşılaştırmak üzere bir meta analiz yaptık. Mortalite, olumsuz sonuçlar ve yan etkiler analiz edildi. Meta-analiz risk oranı (OR) ve %95 güven aralığı (GA) açısından yapıldı. BuLGuLAR: Beş uygun çalışma dahil edilip analiz edildi ve böylece hedef KB olarak sistolik KB (SKB)

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Cite This Article

YOU, C., HUANG, S., LIU, Y., MA, J., MA, L., LI, H. (2022). effects of Intensive Blood Pressure Lowering on Intracerebral Hemorrhage Outcomes: A Meta-Analysis of Randomized Controlled Trials. Turkish Neurosurgery, Cilt: 25 - Sayı: 4, 544–551. https://ajindex.com/articles/616955

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References (1)

  1. Anderson CS, Heeley E, Huang Y, Wang J, Stapf C, Delcourt C: Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. N Engl J Med 368:2355-2365, 2013 2. Anderson CS, Huang Y, Wang JG, Arima H, Neal B, Peng B: Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): A randomised pilot trial. Lancet Neurol 7:391-399, 2008 3. Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) Investigators: Antihypertensive treatment of acute cerebral hemorrhage. Crit Care Med 38:637-648, 2010 4. Arima H, Anderson CS, Wang JG, Huang Y, Heeley E, Neal B: Lower treatment blood pressure is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage. Hypertension 56:852-858, 2010 5. Brott T, Broderick J, Kothari R, Barsan W, Tomsick T, Sauerbeck L, Spilker J, Duldner J, Khoury J: Early hemorrhage growth in patients with intracerebral hemorrhage. Stroke 28: 1-5, 1997 6. Butcher KS, Jeerakathil T, Hill M, Demchuk AM, Dowlatshahi D, Coutts SB: The intracerebral hemorrhage acutely decreasing arterial pressure trial. Stroke 44:620-626, 2013 7. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. Higgins JPT, Green S (eds). Avaiable at: www. cochrane-handbook.org. Last edited March 20, 2011 8. Frontera JA: Blood pressure in intracerebral hemorrhage-- how low should we go? N Engl J Med 368: 2426-2427, 2013 9. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ: Assessing the quality of reports of randomized clinical trials: Is blinding necessary? Control Clin Trial17:1-12, 1996 10. Jennett B, Bond M: Assessment of outcome after severe brain damage. Lancet 1:480-484, 1975 12. Ko SB, Choi HA, Parikh G, Helbok R, Schmidt JM, Lee K: Multimodality monitoring for cerebral perfusion pressure optimization in comatose patients with intracerebral hemorrhage. Stroke 42:3087-3092, 2011 11. Koch S, Romano JG, Forteza AM, Otero CM, Rabinstein AA: Rapid blood pressure reduction in acute intracerebral hemorrhage: Feasibility and safety. Neurocrit Care 8:316-321, 2008 13. Morgenstern LB, Hemphill JC III, Anderson C, Becker K, Broderick JP, Connolly ES Jr: Guidelines for the management of spontaneous intracerebral hemorrhage: A guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 41:2108- 2129, 2010 14. Potter JF, Robinson TG, Ford GA, Mistri A, James M, Chernova J: Controlling hypertension and hypotension immediatel