Journals / Turkish Journal of Veterinary and Animal Sciences / 2002 / Cilt: 26 - Sayı: 4

Long-term administration of alcohol in rats: Effects on glucagon and insulin levels in sera during pre-pregnancy, and lactation periods

Sıçanlara oral yolla uzun süreli uygulanan alkolün gebelik öncesi, gebelik ve laktasyon dönemlerinde serum insülin ve glukagon hormon düzeylerine etkisi

Pages
799–804
Publication Date
2022-11-05
DOI
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Similar results were observed in the experimental group but levels in the experimental group in the pre-pregnancy period were lower than those in the control group, and in the pregnancy phase they were higher (p

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Objective & Hypothesis:The effects of long-term administration of ethyl alcohol on insulin and glucagon hormone levels during pregnancy and lactation periods of rats were investigated.
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Key Findings & Data:Female wistar albinos, 200±20 g, were used in this study.
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Conclusion & Impact:Similar results were observed in the experimental group but levels in the experimental group in the pre-pregnancy period were lower than those in the control group, and in the pregnancy phase they were higher (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The effects of long-term administration of ethyl alcohol on insulin and glucagon hormone levels during pregnancy and lactation periods of rats were investigated. Female wistar albinos, 200±20 g, were used in this study. The control group consisted of 15 rats, and the experimental group consist of 25 ethyl-alcohol-addicted rats. While 0.9% saline (with sucrose) was to the control group, a 5 g kg perday dose of 20% ethyl alcohol was given to the experimental group. Blood samples were taken five times, during the pre-pregnancy (1), pregnancy (3), lactation (1) periods. Insulin and glucagon levels of sera were measured by RIA method. Insulin hormone levels increased until the 3rd trimester in the control group and decreased during subsequent periods. Similar results were observed in the experimental group but levels in the experimental group in the pre-pregnancy period were lower than those in the control group, and in the pregnancy phase they were higher (p

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Cite This Article

ZEYBEK, B., TÜRKMEN, G. (2022). Long-term administration of alcohol in rats: Effects on glucagon and insulin levels in sera during pre-pregnancy, and lactation periods. Turkish Journal of Veterinary and Animal Sciences, Cilt: 26 - Sayı: 4, 799–804. https://ajindex.com/articles/615668

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