Journals / Turkish Journal of Veterinary and Animal Sciences / 2005 / Cilt: 29 - Sayı: 5

Streptozosin indüklü diabetli ratlarda deli balın kan glukoz ve lipid seviyeleri üzerine etkisi

Effect of mad honey on blood glucose and lipid levels in rats with streptozocin-induced diabetes

Pages
1093–1096
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that mad honey caused significant decreases in blood glucose and lipid levels in animals with streptozocin-induced diabetes mellitus (n = 10) and controls (n = 10).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study investigated whether mad honey affects blood glucose and lipid levels in experimental animals.
📊
Key Findings & Data:It was found that mad honey caused significant decreases in blood glucose and lipid levels in animals with streptozocin-induced diabetes mellitus (n = 10) and controls (n = 10).
💡
Conclusion & Impact:These decreases may be due to grayanotoxins in the mad honey causing the islets of Langerhans in the pancreas to secrete insulin by stimulating the parasympathetic nervous system or M2-muscarinic receptors.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study investigated whether mad honey affects blood glucose and lipid levels in experimental animals. It was found that mad honey caused significant decreases in blood glucose and lipid levels in animals with streptozocin-induced diabetes mellitus (n = 10) and controls (n = 10). These decreases may be due to grayanotoxins in the mad honey causing the islets of Langerhans in the pancreas to secrete insulin by stimulating the parasympathetic nervous system or M2-muscarinic receptors.

Özet

Bu çalışmada, deney hayvanlarında deli balın kan glukoz ve lipid seviyeleri üzerine etkisi olup olmadığını araştırmak amaçlanmıştır. Deli balın hem streptozosin indüklü diabetes mellituslu (n = 10) hem de kontrol (n = 10) hayvanlarında kan glukoz ve lipid seviyelerinde anlamlı bir düşmeye sebep olduğu bulundu. Kan glukoz ve lipid seviyelerindeki bu düşüş, deli balda bulunan grayanotoksinlerin parasempatetik sinir sistemini veya M2-muskarinik reseptörleri uyararak pankreas Langerhans adacık hücrelerinden insülin salgılatmasına bağlı olabilir.

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Cite This Article

DANE, Ş., GÖÇER, F., ALTINKAYNAK, K., AKÇAY, F., ÖZTAŞAN, N. (2022). Streptozosin indüklü diabetli ratlarda deli balın kan glukoz ve lipid seviyeleri üzerine etkisi. Turkish Journal of Veterinary and Animal Sciences, Cilt: 29 - Sayı: 5, 1093–1096. https://ajindex.com/articles/615480

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