Journals / Turkish Journal of Veterinary and Animal Sciences / 2006 / Cilt: 30 - Sayı: 6

İnfertil ineklerin tedavisi: $PGF_{2alpha}$ ve gentamisin veya kombinasyonunu PRID rejimindeki etkinliği

Treatment of infertile cows. Efficacy of $PGF_{2alpha}$ and gentamicin or their combination in a PRID regime

Pages
521–525
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The results indicate that the combination of PGF2a and gentamicin in a PRID regime may be useful for the treatment of infertility in cows.

📌 3 Key Takeaways

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Objective & Hypothesis:The efficacy of $PGF_{2alpha}$ and intrauterine gentamicin or their combination in a progesterone releasing intravaginal device (PRID) regime was investigated for treatment of infertility in cows.
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Key Findings & Data:From 46 infertile cows, body condition scores (BCSs) were recorded and the cows were then divided into 4 experimental groups according to the synchronisation protocol and intrauterine gentamicin administration as follows: i) PRID (1.55 g of progesterone and 10 mg of oestradioi benzoate) for 12 days plus artificial insemination (AI) at 48 and 72 h (group 1, n = 8), ii) PRID for 12 days plus an i.m. injection of 0.150 mg of cloprostenol on day 10 and 2 AIs (group 2, n = 10), iii) PRID for 12 days plus 2 AIs and intrauterine 250 mg of gentamicin sulphate after 30 min (group 1)n = 18), and iv) PRID for 12 days plus an injection of cloprostenol on day 10 and gentamicin administration after 2 AIs (group 2)n = 10).
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Conclusion & Impact:The results indicate that the combination of PGF2a and gentamicin in a PRID regime may be useful for the treatment of infertility in cows.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The efficacy of $PGF_{2alpha}$ and intrauterine gentamicin or their combination in a progesterone releasing intravaginal device (PRID) regime was investigated for treatment of infertility in cows. From 46 infertile cows, body condition scores (BCSs) were recorded and the cows were then divided into 4 experimental groups according to the synchronisation protocol and intrauterine gentamicin administration as follows: i) PRID (1.55 g of progesterone and 10 mg of oestradioi benzoate) for 12 days plus artificial insemination (AI) at 48 and 72 h (group 1, n = 8), ii) PRID for 12 days plus an i.m. injection of 0.150 mg of cloprostenol on day 10 and 2 AIs (group 2, n = 10), iii) PRID for 12 days plus 2 AIs and intrauterine 250 mg of gentamicin sulphate after 30 min (group 1)n = 18), and iv) PRID for 12 days plus an injection of cloprostenol on day 10 and gentamicin administration after 2 AIs (group 2)n = 10). Following administrations, the oestrus rates and 60-120 day non-return rates (NRRs) were determined in all cows. The respective oestrus rates in groups 1 to 4 were 75.0 ± 16.4%, 90.0 ± 10.0%, 72.2 ± 10.9% and 100.0 ± 0.0% with no significant differences between them. Likewise, corresponding NRRs were 37.5 ± 18.3%, 30.0 ± 15.3%, 27.8 ± 10.9% and 60.0 ± 16.3%, and there were no significant differences between them. However, the oestrus rates and NRRs were higher in group 4. The results indicate that the combination of PGF2a and gentamicin in a PRID regime may be useful for the treatment of infertility in cows.

Özet

Sunulan çalışmada, ineklerde infertilite vakalarının tedavisi amacıyla uygulanan $PGF_{2alpha}$ ve gentamisin veya kombinasyonun PRİD (progesteron salıcı vagina-içi aygıt) rejimindeki etkinliği araştırıldı. Toplam 46 adet infertil inek, vücut kondisyon skorları belirlenerek dengelendikten sonra, senkronizasyon protokolü ve gentamisin (sülfat) uygulamasına göre dört deney grubuna ayrıldı: i) 12 gün süreyle PRİD (1,55 g progesteron ve 10 mg östradiol benzoat) uygulaması + 48. ve 72. saatlerde suni tohumlama (Grup 1, n = 8), ii) 12 gün süreyle PRİD ve 10. günde 0,150 mg i.m. cloprostenol enjeksiyonu + iki tohumlama (Grup 2, n = 10), iii) 12 gün süreyle PRİD + iki tohumlama ve 30 dakika sonra uterus-içi 250 mg gentamisin sülfat uygulaması (Grup 3, n = 18), ve iv) 12 gün süreyle PRİD ve 10. günde cloprostenol enjeksiyonu + gentamisin uygulaması (Grup 4, n = 10). Uygulamalar sonrası tüm ineklerdeki östrus oranı ve 60-120 günlük geri-dönmeyen oranı (NRR) belirlendi. Çalışma gruplarındaki (1-4) östrus oranları sırasıyla % 75,0 ± 16,4, % 90,0 ± 10,0, % 72,2 ± 10,9 ve % 100,0 ± 0,0 olarak bulunurken, gruplar arası önemli bir farklılık gözlenmedi. NRR değerleri ise sırasıyla % 37,5 ± 18,3, % 30,0 ± 15,3, % 27,8 ± 10,9 ve % 60,0 ± 16,3 olarak bulundu, ancak gruplar arasında önemli bir fark gözlenmedi. Ancak, Grup 4'teki ineklerin östrus oranları ve NRR, sayısal olarak diğer gruplara göre nispeten daha yüksekti. Sonuç olarak, PRİD rejiminde PGF2oı ve gentamisin kombinasyonunun ineklerdeki infertilite olgularını tedavide faydalı olabileceği kanısına varıldı.

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Cite This Article

UÇAR, Ö., ÖZTÜRKLER, Y. (2022). İnfertil ineklerin tedavisi: $PGF_{2alpha}$ ve gentamisin veya kombinasyonunu PRID rejimindeki etkinliği. Turkish Journal of Veterinary and Animal Sciences, Cilt: 30 - Sayı: 6, 521–525. https://ajindex.com/articles/615438

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