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Journals / Turkish Journal of Veterinary and Animal Sciences / 2016 / Cilt: 40 - Sayı: 1

Subarachnoid transplantation of autologous neurogenically induced bone marrow derived mesenchymal stem cells for the treatment of fibrocartilaginous embolic myelopathy in two dogs

Ayşe Eser ELÇİN
Yaşar Murat ELÇİN
Zeynep AKTAŞ
Eylül AKPINAR
Ömer BEŞALTI
Pınar CAN
Pages
120–123
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Based on a 21-month follow-up of the treated animals, the transplantation of NIBM-MSCs seems to be promising in subjects with FCEM lacking DPP.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The objective of this study was to investigate the effects of autologous neurogenically induced bone marrow-derived mesenchymal stem cells (NIBM-MSCs) in two dogs suspected to have fibrocartilaginous embolic myelopathy (FCEM).
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Key Findings & Data:Autologous NIBM-MSCs (5 × 106)were transplanted into the lumbar subarachnoid space two times with a 21-day interval for each patient.
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Conclusion & Impact:Based on a 21-month follow-up of the treated animals, the transplantation of NIBM-MSCs seems to be promising in subjects with FCEM lacking DPP.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The objective of this study was to investigate the effects of autologous neurogenically induced bone marrow-derived mesenchymal stem cells (NIBM-MSCs) in two dogs suspected to have fibrocartilaginous embolic myelopathy (FCEM). Both dogs were paraplegic without deep pain perception (DPP) and tentatively diagnosed by MRI. Autologous NIBM-MSCs (5 × 106)were transplanted into the lumbar subarachnoid space two times with a 21-day interval for each patient. Based on a 21-month follow-up of the treated animals, the transplantation of NIBM-MSCs seems to be promising in subjects with FCEM lacking DPP.

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Cite This Article

ELÇİN, A. E., ELÇİN, Y. M., AKTAŞ, Z., AKPINAR, E., BEŞALTI, Ö., CAN, P. (2022). Subarachnoid transplantation of autologous neurogenically induced bone marrow derived mesenchymal stem cells for the treatment of fibrocartilaginous embolic myelopathy in two dogs. Turkish Journal of Veterinary and Animal Sciences, Cilt: 40 - Sayı: 1, 120–123. https://ajindex.com/articles/615174

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