Journals / Turkish Journal of Veterinary and Animal Sciences / 2021 / Cilt: 45 - Sayı: 5

Identification of novel genetic variants for KAP1.1, KAP1.3 and K33 genes in some of indigenous goat breeds of Turkey

Pages
805–813
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is necessary to determine the relationships with mohair yield, quality and polymorphisms that are determined in KAP1.1, KAP1.3 and KRT1.2 genes.

📌 3 Key Takeaways

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Objective & Hypothesis:The animal fibres such as mohair, cashmere and cashgora have a complex structure and affected by genetic variation of keratin associated protein genes as KAP 1.1 (Keratin Associated Protein 1.1, formerly known as B2A), KAP1.3 (Keratin Associated Protein 1.3, formerly known as B2C) and K33 (Keratin Intermediate Filaments Type I, formerly known as KRT1.2).
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Key Findings & Data:Keratin-associated proteins play a significant role in identifying structural and mechanical properties of the hair and wool fibres.
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Conclusion & Impact:It is necessary to determine the relationships with mohair yield, quality and polymorphisms that are determined in KAP1.1, KAP1.3 and KRT1.2 genes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The animal fibres such as mohair, cashmere and cashgora have a complex structure and affected by genetic variation of keratin associated protein genes as KAP 1.1 (Keratin Associated Protein 1.1, formerly known as B2A), KAP1.3 (Keratin Associated Protein 1.3, formerly known as B2C) and K33 (Keratin Intermediate Filaments Type I, formerly known as KRT1.2). Keratin-associated proteins play a significant role in identifying structural and mechanical properties of the hair and wool fibres. This study was conducted to detect genetic variation at the KAP1.1, KAP1.3 and K33 genes in indigenous Turkish goat populations using DNA sequencing method. The DNA of 100 individuals selected from 5 different native goat breeds (Hair, Honamlı, Kilis, Norduz, and Angora) that reared different regions of Turkey were used as materials. A total of 59 nucleotide variations and indels (insertion/deletion) of KAP1.1 gene, 15 nucleotide variations and indels of KAP1.3 gene, 16 nucleotide variations of K33 gene were determined in the studied samples. These nucleotide variations and indels have been causing changes in the number and sequence of amino acids. It is necessary to determine the relationships with mohair yield, quality and polymorphisms that are determined in KAP1.1, KAP1.3 and KRT1.2 genes.

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Cite This Article

IŞIK, R., ÜNAL, E. Ö., FİDAN, A., SOYSAL, M. İ. (2022). Identification of novel genetic variants for KAP1.1, KAP1.3 and K33 genes in some of indigenous goat breeds of Turkey. Turkish Journal of Veterinary and Animal Sciences, Cilt: 45 - Sayı: 5, 805–813. https://ajindex.com/articles/615083

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