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Journals / Turkish Journal of Veterinary and Animal Sciences / 2022 / Cilt: 46 - Sayı: 3

Investigation of IgG, vimentin, CD45 distribution, and density in mouse placenta at different periods of pregnancy

Seçil KOÇ
Şadiye KUM
Pages
505–516
Publication Date
2022-11-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

While the expression of vimentin was observed in the labyrinth placenta and the MLAp in a granular fashion, CD45 was expressed in a few P-TGCs as well as in MLAp along with vimentin.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to investigate the distribution and density of IgG, vimentin, and CD45 in mouse placenta on the fourth, tenth, and seventeenth days of pregnancy.
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Key Findings & Data:On the fourth day of pregnancy, the expression of IgG, vimentin, and CD45 was more intense around the uterine glands.
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Conclusion & Impact:While the expression of vimentin was observed in the labyrinth placenta and the MLAp in a granular fashion, CD45 was expressed in a few P-TGCs as well as in MLAp along with vimentin.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to investigate the distribution and density of IgG, vimentin, and CD45 in mouse placenta on the fourth, tenth, and seventeenth days of pregnancy. Strept avidin-biotin-peroxidase complex (streptABC) staining method was used. On the fourth day of pregnancy, the expression of IgG, vimentin, and CD45 was more intense around the uterine glands. On the tenth day, IgG, vimentin and CD45 positive cells were demonstrated in decidua basalis and mesometrial parietal trophoblast giant cells (P-TGCs) and mesometrial lymphocyte groups (MLAp) portions. The formation of the placenta was completed on the seventeenth day of pregnancy. The expression of IgG in the labyrinth placenta as well as in the decidual spaces was evident on the seventeenth day of pregnancy. While the expression of vimentin was observed in the labyrinth placenta and the MLAp in a granular fashion, CD45 was expressed in a few P-TGCs as well as in MLAp along with vimentin.

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Cite This Article

KOÇ, S., KUM, Ş. (2022). Investigation of IgG, vimentin, CD45 distribution, and density in mouse placenta at different periods of pregnancy. Turkish Journal of Veterinary and Animal Sciences, Cilt: 46 - Sayı: 3, 505–516. https://ajindex.com/articles/614518

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