Journals / Turkish Journal of Urology / 2018 / Cilt: 44 - Sayı: 3

Asymptomatic bacteriuria and antimicrobial susceptibility pattern of the isolates among pregnant women attending Dessie referral hospital, Northeast Ethiopia: A hospital-based cross-sectional study

Kuzey Doğu Etiyopya’daki Dessie referans hastanesine başvuran gebe kadınlarda asemptomatik bakteriüri ve izolatların antimikrobiyal duyarlılığı: Bir hastane temelli, kesitsel çalışma

Pages
251–260
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Data were analyzed by SPSS version 20 software and in all cases, p-values below 0.05was considered as statistically significant.Results: Overall, 358 pregnant women were included in the study with a mean age of 26.5±4.6 years (range,19-43 yrs).

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of the current study was to find out the prevalence of asymptomatic bacteriuria, antimicrobialsusceptibility pattern of the isolates and related risk factors among pregnant women.Material and methods: A hospital-based cross-sectional study was carried out from February 2017 to May2017 among asymptomatic pregnant mothers attending Dessie Referral Hospital, Northeast Ethiopia.
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Key Findings & Data:About10-15 mL of freshly voided midstream urine samples were collected from each study participants, andanalyzed at Dessie regional research microbiology laboratory with conventional antibiotic susceptibility,and biochemical tests.
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Conclusion & Impact:Data were analyzed by SPSS version 20 software and in all cases, p-values below 0.05was considered as statistically significant.Results: Overall, 358 pregnant women were included in the study with a mean age of 26.5±4.6 years (range,19-43 yrs).
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of the current study was to find out the prevalence of asymptomatic bacteriuria, antimicrobialsusceptibility pattern of the isolates and related risk factors among pregnant women.Material and methods: A hospital-based cross-sectional study was carried out from February 2017 to May2017 among asymptomatic pregnant mothers attending Dessie Referral Hospital, Northeast Ethiopia. About10-15 mL of freshly voided midstream urine samples were collected from each study participants, andanalyzed at Dessie regional research microbiology laboratory with conventional antibiotic susceptibility,and biochemical tests. Isolates were tested against commonly used antimicrobials using Kirby Bauer discdiffusion method. Data were analyzed by SPSS version 20 software and in all cases, p-values below 0.05was considered as statistically significant.Results: Overall, 358 pregnant women were included in the study with a mean age of 26.5±4.6 years (range,19-43 yrs). The overall prevalence of asymptomatic bacteriuria was 56% (15.6%). Isolated microorganismswere mainly Escherichia coli and Staphylococcus aureus (for each, n=18; 31%). Escherichia coli andStaphylococcus aureus were resistant to ampicillin (66.7%), and penicillin (94.44%). The prevalence of multidrug-resistant isolates was 72.4%. History of catheterization [AOR=2.28, 95% CI=(1.03-5.06)] and anemia[AOR=4.98, 95% CI=(2.395-10.34) were statistically significant regarding the prevalence of asymptomaticbacteriuria.Conclusion: The overall prevalence of asymptomatic bacteriuria among pregnant women in the study areawas high. The presence of asymptomatic bacteriuria and their antibiotic susceptibility test results should betaken into consideration during the management of pregnant women who are visiting antenatal care clinic

Özet

Amaç: Bu çalışmanın amacı gebe kadınlarda asemptomatik bakteriüri oranları, izolatların antimikrobiyal duyarlılıklarının ve ilişkin risk faktörlerinin prevalansını saptamaktı. Gereç ve yöntemler: Kuzey Doğu Etiyopya’daki Dessei Referans Hastanesine 2017 Şubat ila 2017 Mayıs arasında başvuran asemptomatik gebe kadınlarda bir hastane temelli kesitsel çalışma yürütülmüştür. Her bir çalışma katlımcısından yaklaşık 10-15 ml yeni işenmiş orta akım idrar örnekleri toplanmış ve Dessie bölgesel araştırma mikrobiyoloji laboratuvarında konvansiyonel antibiyotik duyarlılık ve biyokimyasal testlerle analiz edilmiştir. İzolatlar Kirby-Bauer disk difüzyon yöntemiyle genellikle kullanılan antibiyotiklere karşı test edilmiştir. Veriler SPSS v.20 yazılımı ile analiz edilmiş ve 0.05 altı p değerlerinin statistik açıdan anlamlı olduğu kabul edilmiştir. Bulgular: Yaş ortalaması 26,5±4,6 yıl (19-43 yıl) olan 338 gebe kadın çalışmaya dahil edilmiştir. Asemptomatik bakteriürinin genel prevalansı %56 (%15,6) idi. Başlıca Escherichia coli ve Staphylococcus aureus (her biri için, n=18; %31) izole edilmişti. Escherichia coli and Staphylococcus ampicillin (%66,7) ve penisiline (%94,4) dirençliydi. Çoklu ilaca dirençli izolatların prevalansı %72,4 idi. Asemptomatik bakteriürinin prevalansı açısından kateterizayon öyküsü [AOR=2,28, %95 GA=(1,03-5,06)] ve anemi [AOR=4,98, %95 GA=(2,395-10,34) istatistiksel açıdan anlamlı idi. Sonuç: Çalışmadaki gebe kadınlarda asemptomatik bakteriürinin genel prevalansı yüksek bulundu. Antenatal bakım kliniğini ziyaret eden gebe kadınların tedavi sürecinde asemptomatik bakteriürinin durumu ve antibiyotik duyarlılık test sonuçları dikkate alınmalıdır

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Cite This Article

ALİ, I. E., GEBRECHERKOS, T., GİZACHEW, M., MENBERU, M. A. (2022). Asymptomatic bacteriuria and antimicrobial susceptibility pattern of the isolates among pregnant women attending Dessie referral hospital, Northeast Ethiopia: A hospital-based cross-sectional study. Turkish Journal of Urology, Cilt: 44 - Sayı: 3, 251–260. https://ajindex.com/articles/614392

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