These findings implicated that alpha-2-macroglobulin has no significant role in the pathogenesis of respiratory distress syndrome.
📌 3 Key Takeaways
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Objective & Hypothesis:The vasoactive products of uncontrolled protease activity can play an important role in the pathogenesis of respiratory distress syndrome in newborn infants.
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Key Findings & Data:In this study alpha-2-macroglobulin, which has antiproteolytic activity, was studied in the first few hours of life in preterm infants with and without respiratory distress syndrome.
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Conclusion & Impact:These findings implicated that alpha-2-macroglobulin has no significant role in the pathogenesis of respiratory distress syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
The vasoactive products of uncontrolled protease activity can play an important role in the pathogenesis of respiratory distress syndrome in newborn infants. In this study alpha-2-macroglobulin, which has antiproteolytic activity, was studied in the first few hours of life in preterm infants with and without respiratory distress syndrome. Mean plasma alpha-2-macroglobulin levels were found to be similar in both groups. These findings implicated that alpha-2-macroglobulin has no significant role in the pathogenesis of respiratory distress syndrome.
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Cite This Article
YURDAKÖK, M., YİĞİT, Ş., KİRAZLI, Ş., DÜNDAR, S., GÜRAKAN, B. (2022). Alpha-2-macroglobulin levels in early respiratory distress syndrome. Turkish Journal of Pediatrics, Cilt: 40 - Sayı: 4, 567–570. https://ajindex.com/articles/613541