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Journals / Turkish Journal of Pediatrics / 2015 / Cilt: 57 - Sayı: 5

Can Burkitt's Lymphoma and Hodgkin's Lymphoma occur in siblings simultaneously?

Meriç Kaymak-Cihan1, Olcay Kandemir2, Klara Dalva3, Neriman Sarı4, Nilgün Kurucu4, İnci Ergürhan-İlhan4

İnci ERGÜRHAN-İLHAN
Klara DALVA
Olcay KANDEMİR
Meriç KAYMAK-CİHAN
Neriman SARI
Pages
536–540
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, we have discussed familial lymphoma pathogenesis and HLA haplotypes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Kaymak-Cihan M, Kandemir O, Dalva K, Sarı N, Kurucu N, Ergürhan-İlhan İ.
📊
Key Findings & Data:Turk J Pediatr 2015; 57: 536-540.Familial clustering of Hodgkin lymphoma (HL) and increased risk of developing disease among the siblings has been reported earlier.
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Conclusion & Impact:In addition, we have discussed familial lymphoma pathogenesis and HLA haplotypes.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Kaymak-Cihan M, Kandemir O, Dalva K, Sarı N, Kurucu N, Ergürhan-İlhan İ. Can Burkitt's lymphoma and Hodgkin's lymphoma occur in siblings simultaneously? Turk J Pediatr 2015; 57: 536-540.Familial clustering of Hodgkin lymphoma (HL) and increased risk of developing disease among the siblings has been reported earlier. Usually familial lymphoma in sibling pairs occurs in the pairs of either non-Hodgkin lymphoma or HL. In the familial HL, same type of human leukocyte antigens (HLA) is responsible in the affected family members. There are also some studies stating "Killer cell immunoglobulin like receptor (KIR)" genotypes can be important in the etiology of familial HL. Here we report two siblings; one with Non-Hodgkin and the other with Hodgkin lymphoma which showed Epstein-Barr virus encoded small RNAs positivity in the tumor tissues. We have also found that their HLA genotypes are same with each other. In addition, we have discussed familial lymphoma pathogenesis and HLA haplotypes.

Özet

Kaymak-Cihan M, Kandemir O, Dalva K, Sarı N, Kurucu N, Ergürhan-İlhan İ. Can Burkitt's lymphoma and Hodgkin's lymphoma occur in siblings simultaneously? Turk J Pediatr 2015; 57: 536-540.Familial clustering of Hodgkin lymphoma (HL) and increased risk of developing disease among the siblings has been reported earlier. Usually familial lymphoma in sibling pairs occurs in the pairs of either non-Hodgkin lymphoma or HL. In the familial HL, same type of human leukocyte antigens (HLA) is responsible in the affected family members. There are also some studies stating "Killer cell immunoglobulin like receptor (KIR)" genotypes can be important in the etiology of familial HL. Here we report two siblings; one with Non-Hodgkin and the other with Hodgkin lymphoma which showed Epstein-Barr virus encoded small RNAs positivity in the tumor tissues. We have also found that their HLA genotypes are same with each other. In addition, we have discussed familial lymphoma pathogenesis and HLA haplotypes.

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Cite This Article

ERGÜRHAN-İLHAN, İ., DALVA, K., KANDEMİR, O., KAYMAK-CİHAN, M., SARI, N. (2022). Can Burkitt's Lymphoma and Hodgkin's Lymphoma occur in siblings simultaneously?. Turkish Journal of Pediatrics, Cilt: 57 - Sayı: 5, 536–540. https://ajindex.com/articles/613282

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