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Journals / Turkish Journal of Pediatrics / 2017 / Cilt: 59 - Sayı: 2

Successful treatment of a childhood synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with subcutaneous methotrexate: A case report

Meltem AKÇABOY
Emel ISIYEL
Yaşar KANDUR
Necla BUYAN
Enver HASANOĞLU
Sevcan Azime BAKKALOĞLU EZGÜ
Bahar BÜYÜKKARAGÖZ
Pages
184–188
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report our casein order to take attention to this rare clinical condition in evaluating patientsand also to point out that treatment options beyond biologic agents shouldbe the first line treatment in childhood.

📌 3 Key Takeaways

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Objective & Hypothesis:SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) isdefined as a syndrome that is related to various osteoarticular manifestationsand chronic dermatological conditions especially severe acne.
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Key Findings & Data:We report an 11-year-old girl who suffered from SAPHO syndromeand successfully treated with subcutaneous methotrexate.
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Conclusion & Impact:We report our casein order to take attention to this rare clinical condition in evaluating patientsand also to point out that treatment options beyond biologic agents shouldbe the first line treatment in childhood.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) isdefined as a syndrome that is related to various osteoarticular manifestationsand chronic dermatological conditions especially severe acne. SAPHO syndromeis a rare and unusual clinical entity in childhood and treatment choices arevariable. We report an 11-year-old girl who suffered from SAPHO syndromeand successfully treated with subcutaneous methotrexate. We report our casein order to take attention to this rare clinical condition in evaluating patientsand also to point out that treatment options beyond biologic agents shouldbe the first line treatment in childhood.

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Cite This Article

AKÇABOY, M., ISIYEL, E., KANDUR, Y., BUYAN, N., HASANOĞLU, E., EZGÜ, S. A. B., BÜYÜKKARAGÖZ, B. (2022). Successful treatment of a childhood synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with subcutaneous methotrexate: A case report. Turkish Journal of Pediatrics, Cilt: 59 - Sayı: 2, 184–188. https://ajindex.com/articles/613163

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