Circulating SCUBE1 levels in women with polycystic ovary syndrome

In the present study, we investigatedSCUBE1 levels in lean glucose-tolerant women with PCOS and assessed the possible association between SCUBE1 levels and hormonal and metabolicfeatures of women with PCOS.Materials and Methods: The study population consisted of 90 lean [body mass index (BMI)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Polycystic ovary syndrome (PCOS) is thought to represent an early manifestation of metabolic syndrome, which is associated with cardiovasculardisease.

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Key Findings & Data:Signal peptide-CUB (complement C1r/C1s, Uegf, and Bmp1)-epidermal growth factor domain-containing protein 1 (SCUBE1) is a plateletactivation marker that plays important roles in vascular biology and has been closely linked to cardiovascular events.

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Conclusion & Impact:In the present study, we investigatedSCUBE1 levels in lean glucose-tolerant women with PCOS and assessed the possible association between SCUBE1 levels and hormonal and metabolicfeatures of women with PCOS.Materials and Methods: The study population consisted of 90 lean [body mass index (BMI)

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Objective: Polycystic ovary syndrome (PCOS) is thought to represent an early manifestation of metabolic syndrome, which is associated with cardiovasculardisease. Signal peptide-CUB (complement C1r/C1s, Uegf, and Bmp1)-epidermal growth factor domain-containing protein 1 (SCUBE1) is a plateletactivation marker that plays important roles in vascular biology and has been closely linked to cardiovascular events. In the present study, we investigatedSCUBE1 levels in lean glucose-tolerant women with PCOS and assessed the possible association between SCUBE1 levels and hormonal and metabolicfeatures of women with PCOS.Materials and Methods: The study population consisted of 90 lean [body mass index (BMI)

Özet

Amaç: Polikistik over sendromu (PKOS), kardiyovasküler hastalıkla ilişkili olan metabolik sendromun erken bulgusu olarak düşünülmektedir. Signal peptide-CUB (complement C1r/C1s, Uegf, and Bmp1)-epidermal büyüme faktörü domain-containing protein 1 (SCUBE1) vasküler biyolojide önemli rol oynayan ve kardiyovasküler olaylarla yakından ilişkili olan bir trombosit aktivasyon belirtecidir. Bu çalışmada, normal kilo ve glukoz toleransı olan PKOS’li kadınlarda SCUBE1 düzeyleri ve bu düzeylerin hormonal ve metabolik özellikler arasındaki olası ilişkinin değerlendirmesi amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya normal kiloya sahip [vücut kitle indeksi (VKİ)

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Cite This Article

EROL, O., DERBENT, A. U., ÖZEL, M. K., YILMAZ, N., EREN, E., ELLİDAĞ, H. Y. (2022). Circulating SCUBE1 levels in women with polycystic ovary syndrome. Turkish Journal of Obstetrics and Gynecology, Cilt: 15 - Sayı: 3, 152–158. https://ajindex.com/articles/613018

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