Journals / Turkish Journal of Obstetrics and Gynecology / 2019 / Cilt: 16 - Sayı: 2

Evaluation of serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia

Geç başlangıçlı preeklampside serum kathepsin B, D ve L düzeylerinin değerlendirilmesi

Pages
91–94
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cathepsin B and D maybe promising biomarkers in women with late-onset preeclampsia.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of the study was to assess serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia.Materials and Methods: One hundred forty pregnant women were enrolled in the study, of which 100 subjects were preeclamptic and 40 were healthycontrols.
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Key Findings & Data:Serum concentrations of cathepsin B, D, and L were measured and compared between the preeclamptic and control groups.Results: Cathepsin B and D concentrations were significantly higher in the preeclamptic group compared with the control group.
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Conclusion & Impact:Cathepsin B and D maybe promising biomarkers in women with late-onset preeclampsia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of the study was to assess serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia.Materials and Methods: One hundred forty pregnant women were enrolled in the study, of which 100 subjects were preeclamptic and 40 were healthycontrols. Serum concentrations of cathepsin B, D, and L were measured and compared between the preeclamptic and control groups.Results: Cathepsin B and D concentrations were significantly higher in the preeclamptic group compared with the control group. There was no statisticallysignificant difference between the groups in terms of cathepsin L concentrations. Cathepsin B concentrations were significantly higher in women withpreeclampsia with severe features compared with those with preeclampsia alone.Conclusion: Women with late-onset preeclampsia have significantly higher serum cathepsin B and D concentrations than controls. Cathepsin B and D maybe promising biomarkers in women with late-onset preeclampsia.

Özet

Amaç: Bu çalışmanın amacı geç başlangıçlı preeklampside serum kathepsin B, D ve L düzeylerini değerlendirmektir. Gereç ve Yöntemler: Çalışmaya 100 preeklamptik ve 40 sağlıklı olmak üzere 140 gebe hasta dahil edildi. Kathepsin B, D ve L serum düzeyleri ölçülerek, preeklamptik ve kontrol grupları arasında karşılaştırıldı. Bulgular: Serum kathepsin B ve D düzeyleri preeklamptik grupta kontrol grubu ile karşılaştırıldığında anlamlı olarak daha yüksek saptandı. Kathepsin L düzeyleri açısından gruplar arasında istatistiksel olarak anlamlı bir fark yoktu. Kathepsin B düzeyleri şiddetli preeklampsi bulguları olan kadınlarda diğer preeklamptik olgularla karşılaştırıldığında istatistiksel olarak anlamlı daha yüksek bulundu. Sonuç: Geç başlangıçlı preeklampsili kadınlarda serum kathepsin B ve D düzeyleri kontrol ile karşılaştırıldığında anlamlı olarak daha yüksekti. Geç başlangıçlı preeklampside kathepsin B ve D umut verici biyobelirteçler olabilir.

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Cite This Article

İLHAN, G. A., YILDIZHAN, B. (2022). Evaluation of serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia. Turkish Journal of Obstetrics and Gynecology, Cilt: 16 - Sayı: 2, 91–94. https://ajindex.com/articles/613014

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