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Journals / Turkish Journal of Obstetrics and Gynecology / 2021 / Cilt: 18 - Sayı: 4

The relationship between oxidative stress markers and endometrial hyperplasia: A case-control study

Oksidatif stres belirteçleri ile endometriyal hiperplazi arasındaki ilişki: Bir olgu kontrol çalışması

Ümit GÖRKEM
Engin YILDIRIM
Can TÜRKLER
Ercan YILMAZ
Hülya ALADAĞ
Ömer Yavuz ŞİMŞEK
Pages
298–303
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The total and native thiol levels were higher values in the control group (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Endometrial hyperplasia (EH) is considered an endometrial cancer precursor.
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Key Findings & Data:Materials and Methods: In our prospective case-control study, participants were washed with 5 mL of saline before the endometrial biopsy.
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Conclusion & Impact:The total and native thiol levels were higher values in the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Endometrial hyperplasia (EH) is considered an endometrial cancer precursor. This study aimed to determine the role of oxidative stress and thiol groups with antioxidant properties in EH pathogenesis. Materials and Methods: In our prospective case-control study, participants were washed with 5 mL of saline before the endometrial biopsy. Endometrial washing fluid was taken into microtubules, and thiol and disulfide levels were analyzed using the Ellman reagent. Results: A total of 108 patients were in the EH group and 84 patients in the control group. The total and native thiol levels were higher values in the control group (p

Özet

Amaç: Endometriyal hiperplazi (EH) endometriyum kanseri prekürsörü olarak kabul edilir. EH patogenezinde oksidatif stresin rolünü ve antioksidan özelliği olan tiyol gruplarının rolünü saptamayı hedefledik. Gereç ve Yöntemler: Prospektif olgu kontrol çalışmamızda katılımcılara endometriyal biyopsi yapılmadan önce 5 mL salin ile endometriyal yıkama yapıldı. Endometriyal yıkama sıvısı mikrotübüllere alındı, Ellman reagent kullanılarak tiyol ve disulfid düzeyleri analiz edildi. Bulgular: EH grubunda 108, kontrol grubunda 84 hasta vardı. Toplam tiyol ve doğal tiyol seviyeleri kontrol grubunda daha yüksekti (her ikisi için p

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Cite This Article

GÖRKEM, Ü., YILDIRIM, E., TÜRKLER, C., YILMAZ, E., ALADAĞ, H., ŞİMŞEK, Ö. Y. (2022). The relationship between oxidative stress markers and endometrial hyperplasia: A case-control study. Turkish Journal of Obstetrics and Gynecology, Cilt: 18 - Sayı: 4, 298–303. https://ajindex.com/articles/612892

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