Journals / Turkish Journal of Obstetrics and Gynecology / 2022 / Cilt: 19 - Sayı: 1

Evaluation of dyslipidemia in preeclamptic pregnant women and determination of the predictive value of the hemato-lipid profile: A prospective, cross- sectional, case-control study

Preeklamptik gebelerde dislipideminin değerlendirilmesi ve hemato-lipid profilin prediktif değerinin belirlenmesi: Prospektif, kesitsel, olgu-kontrol çalışması

Pages
7–20
Publication Date
2022-11-06
DOI
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When the study groups were compared in terms of hematological and blood lipid profile; while serum lymphocyte, triglyceride, and total cholesterol levels were significantly higher in the preeclampsia group than in the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we examined the serum hematologic and lipid parameters of pregnant women with preeclampsia and an age- and gestational-age matched normotensive control group.
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Key Findings & Data:Materials and Methods: All patients diagnosed with late-onset preeclampsia or severe preeclampsia between 34 and 40 weeks of gestation at Inonu University Faculty of Medicine between March 2019 and October 2020 were included.
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Conclusion & Impact:When the study groups were compared in terms of hematological and blood lipid profile; while serum lymphocyte, triglyceride, and total cholesterol levels were significantly higher in the preeclampsia group than in the control group (p
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we examined the serum hematologic and lipid parameters of pregnant women with preeclampsia and an age- and gestational-age matched normotensive control group. We also compared the ratios of hemato-lipid parameters defined as systemic inflammatory markers and determined the predictive value of these values in preeclampsia. Materials and Methods: All patients diagnosed with late-onset preeclampsia or severe preeclampsia between 34 and 40 weeks of gestation at Inonu University Faculty of Medicine between March 2019 and October 2020 were included. Results: A total of 253 pregnant women were included in the study period. When the study groups were compared in terms of hematological and blood lipid profile; while serum lymphocyte, triglyceride, and total cholesterol levels were significantly higher in the preeclampsia group than in the control group (p

Özet

Amaç: Bu çalışmada preeklamptik gebeler ile preeklampsi ile komplike olmayan gebelerin serumlarında hematolojik ve lipid parametreleri değerlendirildi. Ayrıca sistemik enflamatuvar marker olarak da tanımlanan hemato-lipid parametrelerin oranları karşılaştırılıp bu oranların preeklampsideki prediktif değeri belirlendi. Gereç ve Yöntemler: Çalışmaya İnönü Üniversitesi Tıp Fakültesi Hastanesi’nde 01.03.2019-01.10.2020 tarihleri arasında gebeliğin 34-40. haftasında geç başlangıçlı preeklampsi ve şiddetli preeklampsi tanısı alan ve çalışma kriterlerine uygun tüm hastalar alınmış olup katılımcıların serum örneklerinde rutin laboratuvar testlerinin yanında lipid profili analizi yapılıp, gebelerin perinatal ve neonatal sonuçları kaydedildi. Bulgular: Çalışma periyodu içinde toplam 253 gebe çalışmaya dahil edildi. Çalışma grupları hematolojik ve kan lipid profili açısından karşılaştırıldığında; preeklampsi grubunda kontrol grubuna göre serum lenfosit, trigliserid ve total kolesterol seviyeleri anlamlı olarak yüksek iken (sırasıyla p

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Cite This Article

Melekoğlu, R., Özdemir, H., Yaşar, Ş., Çelik, N. Z. (2022). Evaluation of dyslipidemia in preeclamptic pregnant women and determination of the predictive value of the hemato-lipid profile: A prospective, cross- sectional, case-control study. Turkish Journal of Obstetrics and Gynecology, Cilt: 19 - Sayı: 1, 7–20. https://ajindex.com/articles/612860

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