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Journals / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 1

Evaluation of myocardial dispersion of repolarization in patients with heart transplantation

Cengiz BURAK
Muhammed SÜLEYMANOĞLU
Çağrı YAYLA
Ümit KERVAN
Serkan ÇAY
Erkan BAYSAL
Pages
212–216
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

From electrocardiograms, Tp-e interval and Tp-e/QTc ratio were calculated and compared between the 2 groups.Results: Noninvasive arrhythmia indicators including Tp-e interval (84.63 ± 14.17 ms vs 71.82 ± 7.47 ms, P < 0.001), Tp-e/QTc ratio(0.19 ± 0.04 vs 0.16 ± 0.02, P < 0.001) and QTc interval except QT interval were significantly higher in transplanted hearts compared tonormal hearts.Conclusion: Patients with heart transplantation have increased myocardial dispersion of repolarization.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: The number of patients with heart transplantation has dramatically increased in the last decade.
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Key Findings & Data:Considerable studieshave suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmuraldispersion of repolarization and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias.
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Conclusion & Impact:From electrocardiograms, Tp-e interval and Tp-e/QTc ratio were calculated and compared between the 2 groups.Results: Noninvasive arrhythmia indicators including Tp-e interval (84.63 ± 14.17 ms vs 71.82 ± 7.47 ms, P < 0.001), Tp-e/QTc ratio(0.19 ± 0.04 vs 0.16 ± 0.02, P < 0.001) and QTc interval except QT interval were significantly higher in transplanted hearts compared tonormal hearts.Conclusion: Patients with heart transplantation have increased myocardial dispersion of repolarization.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: The number of patients with heart transplantation has dramatically increased in the last decade. Considerable studieshave suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmuraldispersion of repolarization and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. Weanalyzed the dispersion of myocardial repolarization using electrocardiographic Tp-e interval and Tp-e/QTc ratio in patients with hearttransplantation.Materials and methods: This observational study included 38 patients (12 female and 26 male) with heart transplantation and 38 wellmatched controls. From electrocardiograms, Tp-e interval and Tp-e/QTc ratio were calculated and compared between the 2 groups.Results: Noninvasive arrhythmia indicators including Tp-e interval (84.63 ± 14.17 ms vs 71.82 ± 7.47 ms, P < 0.001), Tp-e/QTc ratio(0.19 ± 0.04 vs 0.16 ± 0.02, P < 0.001) and QTc interval except QT interval were significantly higher in transplanted hearts compared tonormal hearts.Conclusion: Patients with heart transplantation have increased myocardial dispersion of repolarization.

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Cite This Article

BURAK, C., SÜLEYMANOĞLU, M., YAYLA, Ç., KERVAN, Ü., ÇAY, S., BAYSAL, E. (2022). Evaluation of myocardial dispersion of repolarization in patients with heart transplantation. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 1, 212–216. https://ajindex.com/articles/612794

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References (11)

  1. Kors JA, van Eck HJR, van Herpen G. The meaning of the TpTe interval and its diagnostic value. J Electrocardiol 2008; 41: 575-580
  2. Antzelevitch C, Sicouri S, Di Diego JM, Burashnikov A, Viskin S, Shimizu W, Yan GX, Kowey P, Zhang L. Does Tpeak-Tend provide an index of transmural dispersion of repolarization? Heart Rhythm 2007; 4: 1114-1116; author reply 1116-1119
  3. Perkiomaki JS, Koistinen MJ, Yli-Mayry S, Huikuri HV. Dispersion of QT interval in patients with and without susceptibility to ventricular tachyarrhythmias after previous myocardial infarction. J Am Coll Cardiol 1995; 26: 174-179
  4. Bazett H. An analysis of the time‐relations of electrocardiograms. Annals of Noninvasive Electrocardiology 1997; 2: 177-194
  5. Yan GX, Antzelevitch C. Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. Circulation 1998; 98: 1928-1936
  6. Fish JM, Di Diego JM, Nesterenko V, Antzelevitch C. Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization: implications for biventricular pacing. Circulation 2004; 109: 2136-2142
  7. Xia Y, Liang Y, Kongstad O, Liao Q, Holm M, Olsson B, Yuan S. In vivo validation of the coincidence of the peak and end of the T wave with full repolarization of the epicardium and endocardium in swine. Heart Rhythm 2005; 2: 162-169
  8. Opthof T, Coronel R, Wilms-Schopman FJ, Plotnikov AN, Shlapakova IN, Danilo P Jr., Rosen MR, Janse MJ. Dispersion of repolarization in canine ventricle and the electrocardiographic T wave: Tp-e interval does not reflect transmural dispersion. Heart Rhythm 2007; 4: 341-348
  9. Antzelevitch C, Shimizu W, Yan GX, Sicouri S, Weissenburger J, Nesterenko VV, Burashnikov A, Di Diego J, Saffitz J, Thomas GP. The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart. J Cardiovasc Electrophysiol 1999; 10: 1124-1152
  10. Shimizu M, Ino H, Okeie K, Yamaguchi M, Nagata M, Hayashi K, Itoh H, Iwaki T, Oe K, Konno T et al. T-peak to T-end interval may be a better predictor of high-risk patients with hypertrophic cardiomyopathy associated with a cardiac troponin I mutation than QT dispersion. Clin Cardiol 2002; 25: 335-339
  11. Castro Hevia J, Antzelevitch C, Tornes Barzaga F, Dorantes Sanchez M, Dorticos Balea F, Zayas Molina R, Quinones Perez MA, Fayad Rodriguez Y. Tpeak-Tend and TpeakTend dispersion as risk factors for ventricular tachycardia/ ventricular fibrillation in pa