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Journals / Turkish Journal of Medical Sciences / 1998 / Cilt: 28 - Sayı: 6

The Effects of ACE Inhibition on Central Retinal Artery in Diabetes Mellitus

Serdal ÇELEBİ
Hüseyin ÇELİKER
Harika ÇELEBİ
Ülkü Ö. ÇELİKER
Pages
637–641
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After cilazapril medication, peak systolic blood flow velocity of central retinal artery didn't change, while peak diastolic and mean blood flow velocity increased (p

📌 3 Key Takeaways

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Objective & Hypothesis:Angiotensin converting enzyme (ACE) inhibitors have been known to inhibit the effects of angiotensin II which increases the vascular resistance.
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Key Findings & Data:In this study, we studied the acute effects of a single dose of 2.5 mg oral cilazapril, ACE inhibitor on blood flow velocity and vascular resistance parameters of central retinal artery (CRA) by color Doppler ultrasonography in 17 patients with nonproliferative diabetic retinopathy (NPDR) and compared the effects of the drug with a placebo group including 17 patients with nonproliferative diabetic retinopathy.
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Conclusion & Impact:After cilazapril medication, peak systolic blood flow velocity of central retinal artery didn't change, while peak diastolic and mean blood flow velocity increased (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Central retinal artery · diabetes retinopathy · cilazapril

Abstract

Angiotensin converting enzyme (ACE) inhibitors have been known to inhibit the effects of angiotensin II which increases the vascular resistance. In this study, we studied the acute effects of a single dose of 2.5 mg oral cilazapril, ACE inhibitor on blood flow velocity and vascular resistance parameters of central retinal artery (CRA) by color Doppler ultrasonography in 17 patients with nonproliferative diabetic retinopathy (NPDR) and compared the effects of the drug with a placebo group including 17 patients with nonproliferative diabetic retinopathy. After cilazapril medication, peak systolic blood flow velocity of central retinal artery didn't change, while peak diastolic and mean blood flow velocity increased (p

Özet

Angiotensin converting enzyme (ACE) inhibitors have been known to inhibit the effects of angiotensin II which increases the vascular resistance. In this study, we studied the acute effects of a single dose of 2.5 mg oral cilazapril, ACE inhibitor on blood flow velocity and vascular resistance parameters of central retinal artery (CRA) by color Doppler ultrasonography in 17 patients with nonproliferative diabetic retinopathy (NPDR) and compared the effects of the drug with a placebo group including 17 patients with nonproliferative diabetic retinopathy. After cilazapril medication, peak systolic blood flow velocity of central retinal artery didn't change, while peak diastolic and mean blood flow velocity increased (p

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Cite This Article

ÇELEBİ, S., ÇELİKER, H., ÇELEBİ, H., ÇELİKER, Ü. Ö. (2022). The Effects of ACE Inhibition on Central Retinal Artery in Diabetes Mellitus. Turkish Journal of Medical Sciences, Cilt: 28 - Sayı: 6, 637–641. https://ajindex.com/articles/612667

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