Journals / Turkish Journal of Medical Sciences / 1998 / Cilt: 28 - Sayı: 5

Mannoprotein Adhesin of Candida albicans Germ Tubes

Pages
469–474
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This suggested that the MPA of the hyphal-form cells on the plastic was different from that on the yeast cells responsible for attachment to the BECs.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The production and detection of a mannoprotein adhesin (MPA) of the hyphal-form cells of C. albicans on plastic petri dishes was investigated.
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Key Findings & Data:Using Concanavalin A-coated latex microspheres, the MPA was detected on the plastic surface on which C. albicans produced germ tubes.
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Conclusion & Impact:This suggested that the MPA of the hyphal-form cells on the plastic was different from that on the yeast cells responsible for attachment to the BECs.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Candida albicans · adhesin · germ tube

Abstract

The production and detection of a mannoprotein adhesin (MPA) of the hyphal-form cells of C. albicans on plastic petri dishes was investigated. Using Concanavalin A-coated latex microspheres, the MPA was detected on the plastic surface on which C. albicans produced germ tubes. The adhesin was extracted using dithiothreitol and iodoacetamide. It did not inhibit the adhesion of the yeast-form C. albicans to buccal epithelial cells (BEC). This suggested that the MPA of the hyphal-form cells on the plastic was different from that on the yeast cells responsible for attachment to the BECs.

Özet

The production and detection of a mannoprotein adhesin (MPA) of the hyphal-form cells of C. albicans on plastic petri dishes was investigated. Using Concanavalin A-coated latex microspheres, the MPA was detected on the plastic surface on which C. albicans produced germ tubes. The adhesin was extracted using dithiothreitol and iodoacetamide. It did not inhibit the adhesion of the yeast-form C. albicans to buccal epithelial cells (BEC). This suggested that the MPA of the hyphal-form cells on the plastic was different from that on the yeast cells responsible for attachment to the BECs.

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Cite This Article

VARDAR-ÜNLÜ, G. (2022). Mannoprotein Adhesin of Candida albicans Germ Tubes. Turkish Journal of Medical Sciences, Cilt: 28 - Sayı: 5, 469–474. https://ajindex.com/articles/612581

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