Journals / Turkish Journal of Medical Sciences / 2000 / Cilt: 30 - Sayı: 3

Decreased Placental Adrenomedullin May Play Role in Preeclampsia

Pages
281–283
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Significance was set at p

📌 3 Key Takeaways

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Objective & Hypothesis:Adrenomedullin (AdM) is a novel peptide that elicits a long-lasting vasorelaxant activity.
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Key Findings & Data:Tissue concentration of rat AdM was measured by using reverse-phase high performance liquid chromatography (Cecil 1100).
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Conclusion & Impact:Significance was set at p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Preeclampsia · adrenomedullin · placental pathology.

Abstract

Adrenomedullin (AdM) is a novel peptide that elicits a long-lasting vasorelaxant activity. It is expressed in several tissues, including adrenal medulla, heart, lung, kidneys, and cultured vascular smooth muscle cells. Also in large amounts, it is present in amniotic fluid and cord blood. The aim of this study was to assess placental AdM secretion in preeclampsia. Placental tissues were collected from seven preeclamptic patients and ten healthy gravidas. Tissue concentration of rat AdM was measured by using reverse-phase high performance liquid chromatography (Cecil 1100). Mann Whitney U test was used for statistical significance. Significance was set at p

Özet

Adrenomedullin (AdM) is a novel peptide that elicits a long-lasting vasorelaxant activity. It is expressed in several tissues, including adrenal medulla, heart, lung, kidneys, and cultured vascular smooth muscle cells. Also in large amounts, it is present in amniotic fluid and cord blood. The aim of this study was to assess placental AdM secretion in preeclampsia. Placental tissues were collected from seven preeclamptic patients and ten healthy gravidas. Tissue concentration of rat AdM was measured by using reverse-phase high performance liquid chromatography (Cecil 1100). Mann Whitney U test was used for statistical significance. Significance was set at p

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Cite This Article

YÜREKLİ, M., GÖKDENİZ, R., MENEKŞE, A., BAZOĞLU, N. (2022). Decreased Placental Adrenomedullin May Play Role in Preeclampsia. Turkish Journal of Medical Sciences, Cilt: 30 - Sayı: 3, 281–283. https://ajindex.com/articles/612379

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