Journals / Turkish Journal of Medical Sciences / 2000 / Cilt: 30 - Sayı: 5

The Effects of Allopurinol on Stomach Mucosal Barrier of Rats Subjected to Ischemia-Reperfusion

Pages
449–451
Publication Date
2022-11-05
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

In the sham group, the mucus decreased to a significant extent (p

📌 3 Key Takeaways

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Objective & Hypothesis:The present experimental study was carried out on rats subjected to ischemia and reperfusion.
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Key Findings & Data:Twenty-one Swiss Albino rats, each weighing 200-250 g, were used.
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Conclusion & Impact:In the sham group, the mucus decreased to a significant extent (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Ischemia and reperfusion · stomach mucosal barrier · allopurinol

Abstract

The present experimental study was carried out on rats subjected to ischemia and reperfusion. The effects of allopurinol on mucus, an important component of the stomach mucosal barrier, were investigated. Twenty-one Swiss Albino rats, each weighing 200-250 g, were used. On the control group, no treatment was performed, while the sham operation group was subjected to 30 minutes of ischemia and 20 minutes of reperfusion. Then, stomachs were examined for ulcerative lesions, and ulcer scores were recorded. Mucus content was determined by the Corne method. In the sham group, the mucus decreased to a significant extent (p

Özet

The present experimental study was carried out on rats subjected to ischemia and reperfusion. The effects of allopurinol on mucus, an important component of the stomach mucosal barrier, were investigated. Twenty-one Swiss Albino rats, each weighing 200-250 g, were used. On the control group, no treatment was performed, while the sham operation group was subjected to 30 minutes of ischemia and 20 minutes of reperfusion. Then, stomachs were examined for ulcerative lesions, and ulcer scores were recorded. Mucus content was determined by the Corne method. In the sham group, the mucus decreased to a significant extent (p

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Cite This Article

ÖNEN, A., KURT, D., GÜZEL, C., CEYLAN, K., KANAY, Z. (2022). The Effects of Allopurinol on Stomach Mucosal Barrier of Rats Subjected to Ischemia-Reperfusion. Turkish Journal of Medical Sciences, Cilt: 30 - Sayı: 5, 449–451. https://ajindex.com/articles/612374

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