SavedAdd your journal

Journals / Turkish Journal of Medical Sciences / 2001 / Cilt: 31 - Sayı: 1

Biochemical Bone Markers in Prostate Cancer Patients with Local and Advanced Bone Metastates

İsa ÖZBEY
Yılmaz AKSOY
Fatih AKÇAY
Hülya AKSOY
Pages
65–68
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean concentrations in the group with positive bone metastases than in the group with local disease (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-specific alkaline phosphatase activities and serum prostate specific antigen (PSA).
📊
Key Findings & Data:This study included 20 patients with benign prostate hyperplasia (BPH) and 23 patients with carcinoma, 11 of had with bone metastases.
💡
Conclusion & Impact:The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean concentrations in the group with positive bone metastases than in the group with local disease (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Prostate cancer · Deoxypyridinoline · Bone markers

Abstract

In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-specific alkaline phosphatase activities and serum prostate specific antigen (PSA). This study included 20 patients with benign prostate hyperplasia (BPH) and 23 patients with carcinoma, 11 of had with bone metastases. DPD excretion in urine was significantly greater in prostate cancer patients with bone metastasis than in those with localised prostate cancer or BPH (p0.05). The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean concentrations in the group with positive bone metastases than in the group with local disease (p

Özet

In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-specific alkaline phosphatase activities and serum prostate specific antigen (PSA). This study included 20 patients with benign prostate hyperplasia (BPH) and 23 patients with carcinoma, 11 of had with bone metastases. DPD excretion in urine was significantly greater in prostate cancer patients with bone metastasis than in those with localised prostate cancer or BPH (p0.05). The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean concentrations in the group with positive bone metastases than in the group with local disease (p

🔖

Cite This Article

ÖZBEY, İ., AKSOY, Y., AKÇAY, F., AKSOY, H. (2022). Biochemical Bone Markers in Prostate Cancer Patients with Local and Advanced Bone Metastates. Turkish Journal of Medical Sciences, Cilt: 31 - Sayı: 1, 65–68. https://ajindex.com/articles/612329

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...