Journals / Turkish Journal of Medical Sciences / 2021 / Cilt: 51 - Sayı: 3

Effects of intraoperative blood loss during liver resection on patients’ outcome: a singlecenter experience

Pages
1388–1395
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Favorable outcomes would be obtained with diligent postoperative care.Key words: Liver surgery, operative bleeding, portal triad clamping, low central venous pressure, hemostasis

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Operative bleeding is one of the major determinants of outcome in liver surgery.
📊
Key Findings & Data:Materials and methods: The data of 257 patients who were treated with LR between January 2007 and October 2018 were retrospectively analyzed.
💡
Conclusion & Impact:Favorable outcomes would be obtained with diligent postoperative care.Key words: Liver surgery, operative bleeding, portal triad clamping, low central venous pressure, hemostasis
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Background/aim: Operative bleeding is one of the major determinants of outcome in liver surgery. This study aimed to describe the impact of intraoperative blood loss on the postoperative course of liver resection (LR). Materials and methods: The data of 257 patients who were treated with LR between January 2007 and October 2018 were retrospectively analyzed. LRs were performed via intermittent portal triad clamping (PTC) under low central venous pressure. Results: LRs were performed for 67.7% of patients with a malignant disease and 32.3% of patients with a benign disease. Major LR was performed in 89 patients (34.6%). The mean PTC period was 20.32 min (±13.7). The median intraoperative bleeding amount was 200 mL (5–3500 mL), the 30-day mortality rate was 4.3%, and the morbidity rate was 31.9%. The hospital stay (p = 0.002), morbidity (p = 0.009), and 30-day mortality (p = 0.041) of patients with a bleeding amount of more than 500 mL significantly increased. Conclusion: Surgeons should consider the adverse effects of intraoperative bleeding during liver resection on patients’ outcome. Favorable outcomes would be obtained with diligent postoperative care.Key words: Liver surgery, operative bleeding, portal triad clamping, low central venous pressure, hemostasis

🔖

Cite This Article

KARABULUT, E., ÇALIK, A., DOHMAN, D., OĞUZ, Ş., TOMAS, K., BODUR, M. S., TOPALOĞLU, S., KÜÇÜKASLAN, H. (2022). Effects of intraoperative blood loss during liver resection on patients’ outcome: a singlecenter experience. Turkish Journal of Medical Sciences, Cilt: 51 - Sayı: 3, 1388–1395. https://ajindex.com/articles/611546

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Jarnagin WR, Gonen M, Fong Y, DeMatteo RP, Ben-Porat L et al. Improvement in perioperative outcome after hepatic resection: analysis of 1803 consecutive cases over the past decade. Annals of Surgery 2002
  2. doi: 10.1097/01. SLA.0000029003.66466.B3 2. Topaloglu S, Inci I, Calik A, Aras O, Oztuna F et al. Intensive pulmonary care after liver surgery: a retrospective survey from a single center. Transplantation Proceedings 2013
  3. doi: 10.1016/j.transproceed.2013.02.082 3. Hallet J, Tsang M, Cheng ESW, Habashi R, Kulyk I et al. The impact of perioperative red blood cell transfusions on long-term outcomes after hepatectomy for colorectal liver metastases. Annals of Surgical Oncology 2015
  4. doi: 10.1245/s10434-015-4477-4 4. Eeson G, Karanicolas PJ. Hemostasis and hepatic surgery. Surgical Clinics of North America 2016
  5. doi: 10.1016/j.suc.2015.12.001 5. Gurusamy KS, Li J, Sharma D, Davidson BR. Pharmacological interventions to decrease blood loss and blood transfusion requirements for liver resection. Cochrane Database of Systematic Reviews 2009
  6. CD008085. doi: 10.1002/14651858. CD008085 6. Smyrniotis V, Farantos C, Kostopanagiotou G, Arkadopoulos N. Vascular control during hepatectomy: review of methods and results. World Journal of Surgery 2005
  7. doi: 10.1007/s00268-005-0025-x 7. Ikeda M, Hasegawa K, Sano K, Imamura H, Beck Y et al. The vessel sealing system (LigaSure) in hepatic resection: a randomized controlled trial. Annals of Surgery 2009
  8. doi: 10.1097/SLA.0b013e3181a334f9 8. Patrlj L, Tuorto S, Fong Y. Combined blunt-clamp dissection and LigaSure ligation for hepatic parenchyma dissection: Postcoagulation technique. Journal of the American College of Surgeons 2010
  9. doi: 10.1016/j. jamcollsurg.2009.09.035 9. Topaloglu S, Yesilcicek Calik K, Calik A, Aydın C, Kocyigit S et al. Efficacy and safety of hepatectomy performed with intermittent portal triad clamping with low central venous pressure. BioMed Research International 2013. doi: 10.1155/2013/297971 10. Arslan MK, Aydin C, Topaloglu S, Calik A, Tomas K et al. Incidence of and risk factors for incisional hernia after liver surgery performed with a J-shaped right subcostal incision. The American Surgeon 2017
  10. e49-53.doi: 10.1177/000313481708300204 11. Tomas K, Oguz S, Topaloglu S, Calik A, Arslan M et al. Is it rational to perform liver resection for patients with intermediate and advanced stages of hepato