SavedAdd your journal

Journals / Turkish Journal of Medical Sciences / 2013 / Cilt: 43 - Sayı: 1

The effects of antioxidants on testicular apoptosis and oxidative stress produced by cell phones

Akif KOÇ
Doğan ÜNAL
Reyhan BAYRAK
Ömer Faruk KARATAŞ
Ersin ÇİMENTEPE
Mehmet Erol YILDIRIM
Murat AYDIN
Ömer BAYRAK
Pages
131–137
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, increased apoptosis by cell phones has been shown for the first time in this report.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to determine the probable effects of cellular phone usage on apoptosis and oxidative/antioxidative balance in testicular tissue, and the probable protective role of vitamin C and E on these processes.
📊
Key Findings & Data:Materials and methods: Forty-two male rats were divided into 6 groups: control, antioxidant, calling, stand-by, calling plus antioxidant, and stand-by plus antioxidant.
💡
Conclusion & Impact:In addition, increased apoptosis by cell phones has been shown for the first time in this report.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Key words: Cellular phone · apoptosis · oxidative stress

Abstract

The aim of this study was to determine the probable effects of cellular phone usage on apoptosis and oxidative/antioxidative balance in testicular tissue, and the probable protective role of vitamin C and E on these processes. Materials and methods: Forty-two male rats were divided into 6 groups: control, antioxidant, calling, stand-by, calling plus antioxidant, and stand-by plus antioxidant. Oxidant and antioxidant parameters and apoptotic indexes were studied. Two identical cell phones were used in the calling and stand-by groups. Results: Cell phone usage significantly increased apoptosis in call, but not in the stand-by position, in testicular tissue. Apoptosis produced in the calling mode was significantly more excessive than in the stand-by mode. Oxidative stress was found as high to some extent in both calling and stand-by positions. However, no ameliorating effect of antioxidants could be demonstrated on either apoptosis or oxidative stress. Conclusion: The effects of cell phones on testicular apoptosis and oxidative stress in the calling and stand-by positions and the effects of antioxidants on both injuries have been investigated for the first time. In addition, increased apoptosis by cell phones has been shown for the first time in this report.

Özet

The aim of this study was to determine the probable effects of cellular phone usage on apoptosis and oxidative/antioxidative balance in testicular tissue, and the probable protective role of vitamin C and E on these processes. Materials and methods: Forty-two male rats were divided into 6 groups: control, antioxidant, calling, stand-by, calling plus antioxidant, and stand-by plus antioxidant. Oxidant and antioxidant parameters and apoptotic indexes were studied. Two identical cell phones were used in the calling and stand-by groups. Results: Cell phone usage significantly increased apoptosis in call, but not in the stand-by position, in testicular tissue. Apoptosis produced in the calling mode was significantly more excessive than in the stand-by mode. Oxidative stress was found as high to some extent in both calling and stand-by positions. However, no ameliorating effect of antioxidants could be demonstrated on either apoptosis or oxidative stress. Conclusion: The effects of cell phones on testicular apoptosis and oxidative stress in the calling and stand-by positions and the effects of antioxidants on both injuries have been investigated for the first time. In addition, increased apoptosis by cell phones has been shown for the first time in this report.

🔖

Cite This Article

KOÇ, A., ÜNAL, D., BAYRAK, R., KARATAŞ, Ö. F., ÇİMENTEPE, E., YILDIRIM, M. E., AYDIN, M., BAYRAK, Ö. (2022). The effects of antioxidants on testicular apoptosis and oxidative stress produced by cell phones. Turkish Journal of Medical Sciences, Cilt: 43 - Sayı: 1, 131–137. https://ajindex.com/articles/611121

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. GSMA Head Office. Five rules for creating the perfect mobile storm. Available at http://www.gsma.com/membership/wp- content/uploads/2012/03/Velti_white_paper_Perfect_Mobile_ Storm.pdf. 2. Oral B, Guney M, Ozguner F, Karahan N, Mungan T, Comlekci S et al. Endometrial apoptosis induced by a 900-MHz mobile phone: preventive effects of vitamins E and C. Adv Ther 2006; 23: 957–73. 3. Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Ocak AR. Effect of mobile phone exposure on apoptotic glial cells and status of oxidative stress in rat brain. Electromagn Biol Med 2009; 28: 342–54.
  2. Khaki AA, Tubbs RS, Shoja MM, Rad JS, Khaki A, Farahani RM et al. The effects of an electromagnetic field on the boundary tissue of the seminiferous tubules of the rat: a light and transmission electron microscope study. Folia Morphol (Warsz) 2006; 65: 188–94.
  3. Lee JS, Ahn SS, Jung KC, Kim YW, Lee SK. Effects of 60 Hz electromagnetic field exposure on testicular germ cell apoptosis in mice. Asian J Androl 2004; 6: 29–34. 6. Saygin M, Caliskan S, Karahan N, Koyu A, Gumral N, Uguz A. Testicular apoptosis and histopathological changes induced by a 2.45 GHz electromagnetic field. Toxicol Ind Health 2011; 27: 455–63.
  4. Sarvalues.com, Inc. SAR Values. Available at http://www. sarvalues.com/eu-complete.html. Accessed 16 April 2012. 8. Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988; 34: 497–500. 9. Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121–6.
  5. Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978; 86: 271–8.
  6. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70: 158–69.
  7. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265–75. Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol 2007; 35: 495–516.
  8. Özdemir B, Kaya A, Söğüt Ö, Kaya H, Gökdemir MT, Celebiş O. Oxidative stress status of individuals involved in traffic accidents. Turk J Med Sci 2012; 42: 507–14.
  9. Zhao TY, Zou SP, Knapp PE. Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes. Neurosci Lett 2007; 412: 34–8.
  10. Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Yegin D. Mobile phone exposure does not induce apoptosis on spermatogenesis in rats. Arch Med Res 2008; 39: 40–4.
  11. Yilmaz F, Dasdag