Lung abscess: analysis of the results as community-acquired or nosocomial

Objective & Hypothesis:To assess the etiology, underlying disease, treatment procedures, and mortality rate of lung abscesses by dividing the patients into community-acquired lung abscess (CALA) and nosocomial lung abscess (NLA) subgroups.

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Key Findings & Data:Materials and methods: We reviewed and analyzed data on 62 adult cases of CALA and NLA treated during 2000-2011 at a tertiary university hospital in Turkey.

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Conclusion & Impact:The overall mortality rate was 12.9%.

🔬Design:Review & Systematic Survey

📍Scope:2000-2011 Verileri

⚙️Variables:Key words: Lung abscess · etiology · treatment

Abstract

To assess the etiology, underlying disease, treatment procedures, and mortality rate of lung abscesses by dividing the patients into community-acquired lung abscess (CALA) and nosocomial lung abscess (NLA) subgroups. Materials and methods: We reviewed and analyzed data on 62 adult cases of CALA and NLA treated during 2000-2011 at a tertiary university hospital in Turkey. Results: Of these 62 patients, 44 had CALA and 18 had NLA. Etiologic microorganisms were isolated in 20 of the 44 patients (45.4%) in the CALA group and in 15 of the 18 patients (83.3%) in the NLA group. Among these patients, Staphylococcus aureus (20.0%) and Pseudomonas aeruginosa (26.7%) were the most common microorganisms in the CALA and NLA groups, respectively. Computed tomography-guided drainage was performed in 20 patients in the study and the abscess was cured in 17 (85%) patients. The overall mortality rate was 12.9%. It was 4.5% and 33.3% in the CALA and NLA groups, respectively (P < 0.05). Conclusion: Lung abscess continues to be a significant cause of morbidity and mortality despite appropriate treatment. Medical therapy is started empirically, and so it is important to separate patients into subgroups of CLA or NLA.

Özet

To assess the etiology, underlying disease, treatment procedures, and mortality rate of lung abscesses by dividing the patients into community-acquired lung abscess (CALA) and nosocomial lung abscess (NLA) subgroups. Materials and methods: We reviewed and analyzed data on 62 adult cases of CALA and NLA treated during 2000-2011 at a tertiary university hospital in Turkey. Results: Of these 62 patients, 44 had CALA and 18 had NLA. Etiologic microorganisms were isolated in 20 of the 44 patients (45.4%) in the CALA group and in 15 of the 18 patients (83.3%) in the NLA group. Among these patients, Staphylococcus aureus (20.0%) and Pseudomonas aeruginosa (26.7%) were the most common microorganisms in the CALA and NLA groups, respectively. Computed tomography-guided drainage was performed in 20 patients in the study and the abscess was cured in 17 (85%) patients. The overall mortality rate was 12.9%. It was 4.5% and 33.3% in the CALA and NLA groups, respectively (P < 0.05). Conclusion: Lung abscess continues to be a significant cause of morbidity and mortality despite appropriate treatment. Medical therapy is started empirically, and so it is important to separate patients into subgroups of CLA or NLA.

Keywords

Key words: Lung abscess etiology treatment percutaneous drainage

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Cite This Article

KANBAY, A., DOĞAN, S. A., YILMAZ, İ., BÜYÜKOĞLAN, H., OYMAK, F. S., YILDIRIM, A., GÜLMEZ, İ., DEMİR, R., TUTAR, N. (2022). Lung abscess: analysis of the results as community-acquired or nosocomial. Turkish Journal of Medical Sciences, Cilt: 43 - Sayı: 2, 255–262. https://ajindex.com/articles/611118

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References (13)

Burrell LS. Abscess of the lung. Br Med J 1937; 2: 789–90. Bartlett JG. The role of anaerobic bacteria in lung abscess. Clin Infect Dis 2005; 40: 923–5.
Wang JL, Chen KY, Fang CT, Hsueh PR, Yang PC, Chang SC. Changing bacteriology of adult community-acquired lung abscess in Taiwan: Klebsiella pneumoniae versus anaerobes. Clin Infect Dis 2005; 40: 915–22.
Takayanagi N, Kagiyama N, Ishiguro T, Tokunaga D, Sugita Y. Etiology and outcome of community acquired lung abscess. Respiration 2010; 80: 98–105.
Mori T, Ebe T, Takahashi M, Isonuma H, Ikemoto H, Oguri T. Lung abscess: analysis of 66 cases from 1979 to 1991. Intern Med 1993; 32: 278–84.
American Thoracic Society, Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired ventilator-associated, and healthcareassociated pneumonia. Am J Respir Crit Care Med 2005; 171: 388–416.
Akgül AG, Topçu S, Liman ŞT. Lung abscess. Turkiye Klinikleri J Thor Surg 2012; 5: 52-6 (article in Turkish with English abstract). Hirshberg B, Sklair-Levi M, Nir-Paz R, Ben-Sira L, Krivoruk V, Kramer MR. Factors predicting mortality of patients with lung abscess. Chest 1999; 115: 746–50. Bartlett JG. Anaerobic bacterial infections of the lung. Chest 1987; 91: 901–9. Bartlett JG. Anaerobic bacterial infections of the lung and pleural space. Clin Infect Dis 1993; 16: 248–55.
Hammond JM, Potgieter PD, Hanslo D, Scott H, Roditi D. The etiology and antimicrobial susceptibility patterns of microorganisms in acute community-acquired lung abscess. Chest 1995; 108: 937–41.
Manfredi F, Daly WJ, Behnke RH. Clinical observation of acute Friedlander pneumonia. Ann Intern Med 1963; 58: 642–53.
Dominguez DC, Antony SJ. Actinomyces and Nocardia infections in immunocompromised and nonimmunocompromised patients. J Natl Med Assoc 1999; 91: 35–9.
Santos J, Palacios R, Rivero A, García-Ordóñez MA, Aliaga L, Muniain MA. Nocardiosis in patients with HIV infection. Rev Clin Esp 2002; 202: 375–8.
Pintado V, Gomez-Mampaso E, Fortun J, Cobo J, Navas E, Quereda C et al. Infection with Nocardia species: clinical spectrum of disease and species distribution in Madrid, Spain, 1978–2001. Infection 2002; 30: 338–40.
Candevir A, Kurtaran B, Kibar F, Karakoç E, Aksu HSZ, Taşova Y. Invasive device-associated nosocomial infections of a teaching hospital in Turkey; four years’ experience. Turk J Med Sci 2011; 41: 137–47.
Allewelt M, Schuler P, Bolcskei PL, Mauch H, Lode H. Ampicillin + sulbactam vs clindamycin +/-cephalosporin