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Journals / Turkish Journal of Medical Sciences / 2015 / Cilt: 45 - Sayı: 2

Malondialdehyde and nitric oxide levels and catalase, superoxide dismutase, and glutathione peroxidase levels in maternal blood during diferent trimesters of pregnancy and in the cord blood of newborns

Sevda YÜKSEL
Ayşe Arzu YİĞİT
Pages
454–459
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In cord blood, MDAand NO levels were lower while CAT and GPx activities were higher than in the third trimester of pregnancy.Conclusion: Tese results suggest that the balance of free radical and antioxidant production during pregnancy ensures healthy fetusgrowth and development.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: To determine whether levels of malondialdehyde (MDA), nitric oxide (NO), superoxide dismutase (SOD), glutathioneperoxidase (GPx), and catalase (CAT) change during the 3 trimesters of pregnancy, and to compare the third trimester of pregnancywith newborn cord blood in respect to the levels of MDA, NO, and antioxidant enzymes.Materials and methods: Maternal blood samples were collected at 9 13, 22 26, and 36 40 weeks of gestation.
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Key Findings & Data:Cord blood was collectedat the time of delivery.Results: NO levels and GPx activity were higher in the second and third trimesters than in the frst trimester.
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Conclusion & Impact:In cord blood, MDAand NO levels were lower while CAT and GPx activities were higher than in the third trimester of pregnancy.Conclusion: Tese results suggest that the balance of free radical and antioxidant production during pregnancy ensures healthy fetusgrowth and development.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: To determine whether levels of malondialdehyde (MDA), nitric oxide (NO), superoxide dismutase (SOD), glutathioneperoxidase (GPx), and catalase (CAT) change during the 3 trimesters of pregnancy, and to compare the third trimester of pregnancywith newborn cord blood in respect to the levels of MDA, NO, and antioxidant enzymes.Materials and methods: Maternal blood samples were collected at 9 13, 22 26, and 36 40 weeks of gestation. Cord blood was collectedat the time of delivery.Results: NO levels and GPx activity were higher in the second and third trimesters than in the frst trimester. MDA level was lower in thethird trimester and SOD and CAT activities were lower in the second and third trimesters than the frst trimester. In cord blood, MDAand NO levels were lower while CAT and GPx activities were higher than in the third trimester of pregnancy.Conclusion: Tese results suggest that the balance of free radical and antioxidant production during pregnancy ensures healthy fetusgrowth and development.

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Cite This Article

YÜKSEL, S., YİĞİT, A. A. (2022). Malondialdehyde and nitric oxide levels and catalase, superoxide dismutase, and glutathione peroxidase levels in maternal blood during diferent trimesters of pregnancy and in the cord blood of newborns. Turkish Journal of Medical Sciences, Cilt: 45 - Sayı: 2, 454–459. https://ajindex.com/articles/610936

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