Journals / Turkish Journal of Medical Sciences / 2016 / Cilt: 46 - Sayı: 3

The effect of addition of ketamine to lidocaine on postoperative pain in rhinoplasties

Pages
789–794
Publication Date
2022-11-05
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Addition of ketamine solution to lidocaine for infiltration block during rhinoplasty was successful in decreasing pain during postoperative periods and reducing analgesic consumption during the first 24 h after the operation.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: The objective of this study was to examine the effect of addition of subanesthetic doses of ketamine to an epinephrinelidocaine solution on postoperative pain, analgesic use, and patient comfort during rhinoplasties.
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Key Findings & Data:We evaluated visual pain score, analgesic demand, Wilson sedation score, and antiemetic demand at 5, 15, and 30 min and 1, 2, 4, 6, 8, 16, and 24 h after the operation.
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Conclusion & Impact:Conclusion: Addition of ketamine solution to lidocaine for infiltration block during rhinoplasty was successful in decreasing pain during postoperative periods and reducing analgesic consumption during the first 24 h after the operation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: The objective of this study was to examine the effect of addition of subanesthetic doses of ketamine to an epinephrinelidocaine solution on postoperative pain, analgesic use, and patient comfort during rhinoplasties. Materials and methods: Ninety patients were randomly divided into three groups: Group L, lidocaine with epinephrine; Group K, lidocaine with epinephrine plus ketamine; and Group S (control group), physiological saline solution with epinephrine. The local anesthetic solution was injected as preincisionally with intranasal submucosal infiltration following induction of general anesthesia. We evaluated visual pain score, analgesic demand, Wilson sedation score, and antiemetic demand at 5, 15, and 30 min and 1, 2, 4, 6, 8, 16, and 24 h after the operation. The patient satisfaction score was checked 24 h after the operation. Results: Visual pain score was significantly reduced in Group K in comparison with the other groups and this group did not need any rescue analgesics (P < 0.05). The postoperative patient satisfaction scores were highest in Group K compared with the other groups (P < 0.05). Conclusion: Addition of ketamine solution to lidocaine for infiltration block during rhinoplasty was successful in decreasing pain during postoperative periods and reducing analgesic consumption during the first 24 h after the operation.

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Cite This Article

YOLOĞLU, S., KAYHAN, G. E., UÇAR, M., ŞANLI, M., GÜLHAŞ, N., BİLEN, B. T., AYTEKİN, A. H. (2022). The effect of addition of ketamine to lidocaine on postoperative pain in rhinoplasties. Turkish Journal of Medical Sciences, Cilt: 46 - Sayı: 3, 789–794. https://ajindex.com/articles/610811

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References (13)

  1. Elyassi H, Mousavinasab M, Rambod M, Hashemian MR, Dabbagh A. The effects of anesthesia method on throat pain after elective rhinoplasty. Int J Prev Med 2011; 2: 275-279
  2. Liao BS, Hilsinger RL Jr, Rasgon BM, Matsuoka K, Adour KK. A preliminary study of cocaine absorption from the nasal mucosa. Laryngoscope 1999; 109: 98-102
  3. Thevasagayam M, Jindal M, Allsop P, Oates J. Does epinephrine infiltration in septoplasty make any difference? A double blind randomised controlled trial. Eur Arch Otorhinolaryngol 2007; 264: 1175-1178
  4. Werdehausen R, Braun S, Hermanns H, Kremer D, Küry P, Hollmann MW, Bauer I, Stevens MF. The influence of adjuvants used in regional anesthesia on lidocaine-induced neurotoxicity in vitro. Reg Anesth Pain Med 2011; 36: 436-443
  5. Kadic L, Niesten E, Heijnen I, Hofmans F, Wilder-Smith O, Driessen JJ, Malefijt MC. The effect of addition of pregabalin and s-ketamine to local infiltration analgesia on the knee function outcome after total knee arthroplasty. Acta Anaesthesiol Belg 2012; 63: 111-114
  6. Mossetti V, Vicchio N, Ivani G. Local anesthetics and adjuvants in pediatric regional anesthesia. Curr Drug Targets 2012; 13: 952-960
  7. Tan PH, Cheng JT, Kuo CH, Tseng FJ, Chung HC, Wu JI, Hsiao HT, Yang LC. Preincisional subcutaneous infiltration of ketamine suppresses postoperative pain after circumcision surgery. Clin J Pain 2007; 23: 214-218
  8. Papaziogas B, Argiriadou H, Papagiannopoulou P, Pavlidis T, Georgiou M, Sfyra E, Papaziogas T. Preincisional intravenous low-dose ketamine and local infiltration with ropivacaine reduces postoperative pain after laparoscopic cholecystectomy. Surg Endosc 2001; 15: 1030-1033
  9. Mathisen LC, Aasbø V, Raeder J. Lack of pre-emptive analgesic effect of [R]-ketamine in laparoscopic cholecystectomy. Acta Anaesthesiol Scand 1999; 43: 220-224
  10. Mottura AA. The tumescent technique for face lifts? Plast Reconstr Surg 1995; 96: 231-232
  11. Demiraran Y, Ozturk O, Guclu E, Iskender A, Ergin MH, Tokmak AS. Vasoconstriction and analgesic efficacy of locally infiltrated levobupivacaine for nasal surgery. Anesth Analg 2008; 106: 1008-1011
  12. Granier M, Dadure C, Bringuier S, Bonnet-Boyer MC, Ryckwaert Y, Loriaux E, Capdevila X. Intranasal lidocaine plus naphazoline nitrate improves surgical conditions and perioperative analgesia in septorhinoplasty surgery. Can J Anaesth 2009; 56: 102-108
  13. Olsha O, Feldman Odenheimer DB, Frankel D. Local anesthesia for inguinal hernia repair in adolescents.