SavedAdd your journal

Journals / Turkish Journal of Medical Sciences / 2016 / Cilt: 46 - Sayı: 1

Minor salivary gland evaluation: Sjögren?s syndrome

Ahmet Merih BİRLİK
Ülkü KÜÇÜK
İsmail SARI
Pınar ÇETİN
Sülen SARIOĞLU
Pages
63–65
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: For 22 of the 69 patients, all 3 sections were scored at

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: We aimed to analyze the value of 3 serial sections, spaced 200 µm apart, for quantification of lymphocyte and plasma cell foci in minor salivary gland biopsy (MSGB).
📊
Key Findings & Data:Materials and methods: Labial MSGBs from 69 patients with Sjögren s syndrome (SS) and scleroderma were used for this study.
💡
Conclusion & Impact:Results: For 22 of the 69 patients, all 3 sections were scored at
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: We aimed to analyze the value of 3 serial sections, spaced 200 µm apart, for quantification of lymphocyte and plasma cell foci in minor salivary gland biopsy (MSGB). Materials and methods: Labial MSGBs from 69 patients with Sjögren s syndrome (SS) and scleroderma were used for this study. Each sample was prepared as 3 serial sections spaced 200 µm apart. Lymphocytic and plasma cell focus score (LFS, PFS) were determined for each section, and the diagnostic results were compared to those obtained from a single section. Results: For 22 of the 69 patients, all 3 sections were scored at

🔖

Cite This Article

BİRLİK, A. M., KÜÇÜK, Ü., SARI, İ., ÇETİN, P., SARIOĞLU, S. (2022). Minor salivary gland evaluation: Sjögren?s syndrome. Turkish Journal of Medical Sciences, Cilt: 46 - Sayı: 1, 63–65. https://ajindex.com/articles/610752

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Al-Hashimi I, Wright JM, Cooley CA, Nunn ME. Reproducibility of biopsy grade in Sjögren’s syndrome. J Oral Pathol Med 2001; 30: 408–412
  2. Morbini P, Manzo A, Caporali R, Epis O, Villa C, Tinelli C, Solcia E, Montecucco C. Multilevel examination of minor salivary gland biopsy for Sjögren’s syndrome significantly improves diagnostic performance of AECG classification criteria. Arthritis Res Ther 2005; 7: 343–348
  3. Greenspan JS, Daniels TE, Talal N, Sylvester RA. The histopathology of Sjögren’s syndrome in labial salivary gland biopsies. Oral Surg Oral Med O 1974; 37: 217–229
  4. Chisholm DM, Mason DK. Labial salivary gland biopsy in Sjögren’s disease. J Clin Pathol 1968; 21: 656–660
  5. Manthorpe R. Sjögren’s syndrome criteria. Ann Rheum Dis 2002; 61: 482–484
  6. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, Daniels TE, Fox PC, Kassan SS, Pillemer SR et al. Classification criteria for Sjögren’s syndrome: a revised version of the European criteria proposed by the American–European Consensus Group. Ann Rheum Dis 2002; 61: 554–558
  7. Vivino FB, Gala I, Hermann GA. Chance in final diagnosis on second evaluation of labial minor salivary gland biopsies. J Rheumatol 2002; 29: 938–944
  8. Scardina GA, Spanó G, Carini F, Spicola M, Valenza V, Messina P, Maresi E. Diagnostic evaluation of serial sections of labial salivary gland biopsies in Sjögren’s syndrome. Med Oral Patol Oral 2007; 12: 565–568
  9. Manz RA, Arce S, Cassese G, Hauser AE, Hiepe F, Radbruch A. Humoral immunity and long-lived plasma cells. Curr Opin Immunol 2002; 14: 517–521
  10. Odendahl M, Jacobi A, Hansen A, Feist E, Hiepe F, Burmester GR, Lipsky PE, Radbruch A, Dörner T. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J Immunol 2000; 165: 5970–5979
  11. Szyszko EA, Brokstad KA, Øijordsbakken G, Jonsson MV, Jonsson R, Skarstein K. Salivary glands of primary Sjögren’s syndrome patients express factors vital for plasma cell survival. Arthritis Res Ther 2011; 13: R2.