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Journals / Turkish Journal of Medical Sciences / 2017 / Cilt: 47 - Sayı: 3

The influence of intraabdominal pressure on the mortality rate of patients with acute pancreatitis

Petar SVORCAN
Maja STOJANOVIC
Predrag STEVANOVIC
Aleksadar KARAMARKOVIC
Radmilo JANKOVIC
Nebojsa LADJEVIC
Pages
748–753
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: IAP has an impact on the increase of mortality rates in patients with acute pancreatitis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Intraabdominal hypertension (IAH) is a common clinical finding in patients with acute pancreatitis and is associated with poor prognosis.
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Key Findings & Data:This study aimed to determine the impact of intraabdominal pressure (IAP) on the mortality rate in patients with acute pancreatitis in an intensive care unit.
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Conclusion & Impact:Conclusion: IAP has an impact on the increase of mortality rates in patients with acute pancreatitis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: Intraabdominal hypertension (IAH) is a common clinical finding in patients with acute pancreatitis and is associated with poor prognosis. This study aimed to determine the impact of intraabdominal pressure (IAP) on the mortality rate in patients with acute pancreatitis in an intensive care unit. Materials and methods: A total of 50 patients with acute pancreatitis were included in this prospective cohort study. Based on the obtained values of IAP, the patients were divided into two groups: those with normal IAP (n = 14) and increased IAP (n = 36). Mean values of IAP were compared with examined variables. Results: The mortality rate of the study group was 40%. Comparing the IAP and treatment outcomes, it was proved that there were statistically highly significant differences (P = 0.012). Increasing the value of IAP increased the mortality rate. Deceased patients in the IAH group had greater statistical significance of APACHE II score (P = 0.016), abdominal perfusion pressure (P = 0.048), lactate (P = 0.049), hematocrit (P = 0.039), Ranson s criteria on admission (P = 0.017), Ranson s criteria after 48 h (P = 0.010), Sequential Organ Failure Assessment score (P = 0.014), and body mass index (P = 0.012) compared to the surviving patients. Conclusion: IAP has an impact on the increase of mortality rates in patients with acute pancreatitis.

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Cite This Article

SVORCAN, P., STOJANOVIC, M., STEVANOVIC, P., KARAMARKOVIC, A., JANKOVIC, R., LADJEVIC, N. (2022). The influence of intraabdominal pressure on the mortality rate of patients with acute pancreatitis. Turkish Journal of Medical Sciences, Cilt: 47 - Sayı: 3, 748–753. https://ajindex.com/articles/610574

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