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Journals / Turkish Journal of Medical Sciences / 2017 / Cilt: 47 - Sayı: 2

The effect of transcatheter aortic valve implantation on mean platelet volume

Kemal Eşref ERDOĞAN
Cenk SARI
Serdal BAŞTUĞ
Abdullah Nabi ASLAN
Mehmet Burak ÖZEN
Bilge DURAN KARADUMAN
Hüseyin AYHAN
Hacı Ahmet KASAPKARA
Telat KELEŞ
Tahir DURMAZ
Engin BOZKURT
Pages
385–390
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We have sought to propound the change in MPV as an indication of endothelial function after TAVI.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Transcatheter aortic valve implantation (TAVI) is an innovative approach to the treatment of aortic stenosis (AS) as an alternative to surgery in high-risk patients.
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Key Findings & Data:Materials and methods: This study included 100 patients diagnosed with symptomatic severe AS and treated with TAVI between July 2011 and August 2013.
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Conclusion & Impact:We have sought to propound the change in MPV as an indication of endothelial function after TAVI.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Background/aim: Transcatheter aortic valve implantation (TAVI) is an innovative approach to the treatment of aortic stenosis (AS) as an alternative to surgery in high-risk patients. Mean platelet volume (MPV) is considered an indicator of endothelial dysfunction, platelet function, and activation. In this study, we aimed to investigate MPV changes in patients undergoing TAVI. Materials and methods: This study included 100 patients diagnosed with symptomatic severe AS and treated with TAVI between July 2011 and August 2013. Hematological parameters of the patients were examined prior to the procedure and 24 h, 1 month, and 6 months after TAVI. Results: A statistically significant change in patients MPV was detected after TAVI compared to the baseline situation (P: 0.001). While no statistically significant change was observed on the first day after TAVI, at discharge, compared to the baseline situation, a statistically significant decrease was seen 1 month and 6 months after discharge. Conclusion: We have demonstrated a decrease in MPV after surgery compared to the value before surgery. We have sought to propound the change in MPV as an indication of endothelial function after TAVI.

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Cite This Article

ERDOĞAN, K. E., SARI, C., BAŞTUĞ, S., ASLAN, A. N., ÖZEN, M. B., KARADUMAN, B. D., AYHAN, H., KASAPKARA, H. A., KELEŞ, T., DURMAZ, T., BOZKURT, E. (2022). The effect of transcatheter aortic valve implantation on mean platelet volume. Turkish Journal of Medical Sciences, Cilt: 47 - Sayı: 2, 385–390. https://ajindex.com/articles/610455

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