Journals / Turkish Journal of Medical Sciences / 2018 / Cilt: 48 - Sayı: 2

The association of neuropathic pain and disease activity, functional level, and quality of life in patients with ankylosing spondylitis: a cross-sectional study

Pages
257–265
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients were divided into two groups.Group 1 included patients with possible or likely NP symptoms (painDETECT score of ≥13) and Group 2 included patients without NPsymptoms (painDETECT score of

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Increased neuropathic pain (NP) symptoms are seen in rheumatologic diseases such as fibromyalgia, osteoarthritis,and rheumatoid arthritis, but no studies have demonstrated a relationship between ankylosing spondylitis (AS) and NP except for abrain imaging study.
📊
Key Findings & Data:The aim of this study was to estimate the presence of NP in patients with AS and to investigate how NP was relatedto disease activity, functional status, and quality of life.Materials and methods: A total of 100 AS patients (71 males and 29 females; median age: 37 years, range: 18–71 years) were included inthe study.
💡
Conclusion & Impact:Patients were divided into two groups.Group 1 included patients with possible or likely NP symptoms (painDETECT score of ≥13) and Group 2 included patients without NPsymptoms (painDETECT score of
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: Increased neuropathic pain (NP) symptoms are seen in rheumatologic diseases such as fibromyalgia, osteoarthritis,and rheumatoid arthritis, but no studies have demonstrated a relationship between ankylosing spondylitis (AS) and NP except for abrain imaging study. The aim of this study was to estimate the presence of NP in patients with AS and to investigate how NP was relatedto disease activity, functional status, and quality of life.Materials and methods: A total of 100 AS patients (71 males and 29 females; median age: 37 years, range: 18–71 years) were included inthe study. Pain (visual analog scale (VAS) and the painDETECT questionnaire), disease activity (Bath Ankylosing Spondylitis DiseaseActivity Index (BASDAI), Maastricht Ankylosing Spondylitis Enthesitis Score (MASES), Patient Global Assessment of Disease Activity(PGA), and Ankylosing Spondylitis Disease Activity Score (ASDAS)), functional level (Bath Ankylosing Spondylitis Functional Index(BASFI)), and health-related quality of life (36-Item Short Form Survey (SF-36)) were evaluated. Patients were divided into two groups.Group 1 included patients with possible or likely NP symptoms (painDETECT score of ≥13) and Group 2 included patients without NPsymptoms (painDETECT score of

🔖

Cite This Article

GELER-KÜLCÜ, D., ÖZTÜRK, G., MESCİ, N., BATIBAY, S. (2022). The association of neuropathic pain and disease activity, functional level, and quality of life in patients with ankylosing spondylitis: a cross-sectional study. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 2, 257–265. https://ajindex.com/articles/610370

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Khan MA. Ankylosing spondylitis: introductory comments on its diagnosis and treatment. Ann Rheum Dis 2002; 61: 3-7.
  2. Baron R, Binder A. How neuropathic is sciatica? The mixed pain concept. Orthopade 2004; 33: 568-575.
  3. Freynhagen R, Baron R, Tolle T, Stemmler E, Gockel U, Stevens M, Maier C. Screening of neuropathic pain components in patients with chronic back pain associated with nerve root compression: a prospective observational pilot study (MIPORT). Curr Med Res Opin 2006; 22: 529-537.
  4. Treede RD, Jensen TS, Campbell JN, Cruccu G, Dostrovsky JO, Griffin JW, Hansson P, Hughes R, Nurmikko T, Serra J. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology 2008; 70: 1630-1635. Woolf CJ. What is this thing called pain? J Clin Invest 2010; 120: 3742-3744.
  5. Amris K, Jespersen A, Bliddal H. Self-reported somatosensory symptoms of neuropathic pain in fibromyalgia and chronic widespread pain correlate with tender point count and pressure-pain thresholds. Pain 2010; 151: 664-669.
  6. Rehm S, Koroschetz J, Gockel U. A cross-sectional survey of 3035 patients with fibromyalgia: subgroups of patients with typical comorbidities and sensory symptom profiles. Rheumatology 2010; 49: 1146-1152.
  7. Hochman JR, French MR, Bermingham SL, Hawker GA. The nerve of osteoarthritis pain. Arthritis Care Res 2010; 62: 1019- 1023. Hochman JR, Gagliese L, Davis AM, Hawker GA. Neuropathic pain symptoms in a community knee OA cohort. Osteoarthr Cartil 2011; 19: 647-655.
  8. Ahmed S, Magan T, Vargas M, Harrison A, Sofat N. Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. J Pain Res 2014; 14: 579-688. Koop SM, ten Klooster PM, Vonkeman HE, Steunebrink LM, van de Laar MA. Neuropathic-like pain features and crosssectional associations in rheumatoid arthritis. Arthritis Res Ther 2015; 3: 237. Wu Q, Inman RD, Davis KD. Neuropathic pain in ankylosing spondylitis a psychophysics and brain imaging study. Arthritis Rheum 2013; 65: 1494-1503. De Vlam K. Soluble and tissue biomarkers in ankylosing spondylitis. Best Pract Res Clin Rheumatol 2010; 24: 671-682.
  9. Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 1994; 21: 2286-2291.
  10. Freynhagen R, Baron R, Gockel U, Tölle TR. painDETECT: a new screening questionnaire to detect neuropathic components in