We investigatedthe relation between CAG and GGN repeats in the AR gene with development of penis length in boys with isolated micropenis.Materials and methods: A total of 24 Turkish boys with isolated micropenis (
📌 3 Key Takeaways
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Objective & Hypothesis:Background/aim:In micropenis cases accompanied by external genital abnormalities such as hypospadias and cryptorchidism, infertilityand spermatogenic failures have been reported to correlate with androgen receptor (AR) gene CAG and GGN repeat polymorphisms.While there is one study on isolated micropenis and CAG repeats, no study related to GGN repeats has been reported.
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Key Findings & Data:Background/aim:In micropenis cases accompanied by external genital abnormalities such as hypospadias and cryptorchidism, infertilityand spermatogenic failures have been reported to correlate with androgen receptor (AR) gene CAG and GGN repeat polymorphisms.While there is one study on isolated micropenis and CAG repeats, no study related to GGN repeats has been reported.
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Conclusion & Impact:We investigatedthe relation between CAG and GGN repeats in the AR gene with development of penis length in boys with isolated micropenis.Materials and methods: A total of 24 Turkish boys with isolated micropenis (
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Background/aim:In micropenis cases accompanied by external genital abnormalities such as hypospadias and cryptorchidism, infertilityand spermatogenic failures have been reported to correlate with androgen receptor (AR) gene CAG and GGN repeat polymorphisms.While there is one study on isolated micropenis and CAG repeats, no study related to GGN repeats has been reported. We investigatedthe relation between CAG and GGN repeats in the AR gene with development of penis length in boys with isolated micropenis.Materials and methods: A total of 24 Turkish boys with isolated micropenis (
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Cite This Article
PERÇİN, E. F., ERGÜN, M. A., TUĞ, E., ERGÜN, S. G., DİLEK, F. N. (2022). The relation between isolated micropenis in childhood with CAG and GGN repeat polymorphisms in the androgen receptor gene. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 2, 430–434. https://ajindex.com/articles/610316
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