Pulmonary valve replacement in patients with repaired tetralogy of Fallot: early results for recovery of right ventricular dilatation and QRS duration

Normalization of RV diameters was found to be independent of ageat PVR, interval between TOF repair and PVR, preoperative QRS duration, and preoperative RV-EDDI.Conclusion: Significant improvement in RV diameter and symptoms could be obtained with PVR in patients with severe pulmonaryregurgitation.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: Although pulmonary valve replacement (PVR) improves ventricular function and symptoms, the benefit and optimaltiming of PVR are controversial.

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Key Findings & Data:This study aimed to evaluate early response to PVR for right ventricle (RV) dilatation and QRS duration.Materials and methods: Retrospective analysis was performed for 32 patients with repaired tetralogy of Fallot (TOF) between March2005 and October 2017.

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Conclusion & Impact:Normalization of RV diameters was found to be independent of ageat PVR, interval between TOF repair and PVR, preoperative QRS duration, and preoperative RV-EDDI.Conclusion: Significant improvement in RV diameter and symptoms could be obtained with PVR in patients with severe pulmonaryregurgitation.

🔬Design:Research Article

📍Scope:2017 Verileri

⚙️Variables:Domain Parameters

Abstract

Background/aim: Although pulmonary valve replacement (PVR) improves ventricular function and symptoms, the benefit and optimaltiming of PVR are controversial. This study aimed to evaluate early response to PVR for right ventricle (RV) dilatation and QRS duration.Materials and methods: Retrospective analysis was performed for 32 patients with repaired tetralogy of Fallot (TOF) between March2005 and October 2017. The differences between preoperative and postoperative changes in echocardiographic parameters, clinicalsymptoms, and QRS duration were evaluated.Results: There were no in-hospital or late deaths. Mean age at the time of PVR was 16.57 ± 7.97 years. The interval between TOF repairand PVR was 12.99 ± 7.06 years. Postoperative echocardiographic findings showed significant reduction in indexed RV end-diastolicdiameter (RV-EDDI) and the ratio of RV/LV-EDDI (P = 0.001 and P = 0.001, respectively). Higher preoperative RV-EDDI was associatedwith decreased change in RV-EDDI after PVR (r = 0.63; P = 0.001). Normalization of RV diameters was found to be independent of ageat PVR, interval between TOF repair and PVR, preoperative QRS duration, and preoperative RV-EDDI.Conclusion: Significant improvement in RV diameter and symptoms could be obtained with PVR in patients with severe pulmonaryregurgitation.

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Cite This Article

SARIOĞLU, T., ALTUN, D., ARNAZ, A., OKTAY, A., YALÇINBAŞ, Y., AKANSEL, S., SERBAN, P., SARIOĞLU, A., DOĞAN, A., SAYGILI, A. (2022). Pulmonary valve replacement in patients with repaired tetralogy of Fallot: early results for recovery of right ventricular dilatation and QRS duration. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 6, 1121–1128. https://ajindex.com/articles/610287

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