Journals / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 3

Viral prevalence, clinical profiles and comparison of severity scores for predicting the mortality of adults with severe acute respiratory infections

Pages
862–871
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therewas no significant difference among these scores in terms of other multivariate comparisons.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: The aim of this study was to determine the accuracy of severity scores for predicting the 28-day mortality amongadults with severe acute respiratory infection (SARI) admitted to the emergency department.Materials and methods: This study included 159 consecutive adult patients with SARI admitted to the emergency department of atertiary hospital.
📊
Key Findings & Data:CURB-65, PSI, SIRS, qSOFA, SOFA and APACHE II scores were compared between the survivorand nonsurvivor groups.Results: Of 159 patients included in the study, 38.4% were positive for respiratory viruses and 28.3% were positive for influenza viruses.35.8% of the patients were admitted to an intensive care unit (ICU) and the mortality rate was 36.5%.
💡
Conclusion & Impact:Therewas no significant difference among these scores in terms of other multivariate comparisons.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: The aim of this study was to determine the accuracy of severity scores for predicting the 28-day mortality amongadults with severe acute respiratory infection (SARI) admitted to the emergency department.Materials and methods: This study included 159 consecutive adult patients with SARI admitted to the emergency department of atertiary hospital. A standard form was filled out in order to record demographic information, clinical parameters, laboratory tests, andradiographic findings of the patients. CURB-65, PSI, SIRS, qSOFA, SOFA and APACHE II scores were compared between the survivorand nonsurvivor groups.Results: Of 159 patients included in the study, 38.4% were positive for respiratory viruses and 28.3% were positive for influenza viruses.35.8% of the patients were admitted to an intensive care unit (ICU) and the mortality rate was 36.5%. The area under the receiveroperating characteristic curve of CURB-65, PSI, SIRS criteria, qSOFA, SOFA and APACHE II scores were 0.717, 0.712, 0.607, 0.683,0.755, and 0.748, respectively in predicting mortality and 0.759, 0.744, 0.583, 0.728, 0.741, and 0.731, respectively in predicting ICUadmission.Conclusion: SOFA and APACHE II were more accurate than SIRS in predicting the 28-day mortality among adults with SARI. Therewas no significant difference among these scores in terms of other multivariate comparisons.

🔖

Cite This Article

ÖZÜÇELİK, D. N., GÜL, O. A., AYDIN, H., KOÇAK, M., DOĞAN, H. (2022). Viral prevalence, clinical profiles and comparison of severity scores for predicting the mortality of adults with severe acute respiratory infections. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 3, 862–871. https://ajindex.com/articles/610101

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Willams BG, Gouws E, Boschi-Pinto C, Bryce J, Dye C. Estimates of World-wide distribibution of child deaths from acute respiratory infections. The Lancet Infectious Diseases 2002
  2. 2 (1): 25-32. doi.org/10.1016/S1473-3099(01)00170-0 2. World Health Organization. Global Epidemiological Surveillance Standards for Influenza. Geneva, Switzerland: WHO Library Cataloguing
  3. Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clinical Infectious Diseases 2007
  4. https://doi.org/10.1086/511159 4. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992
  5. doi. org/10.1378/chest.101.6.1644 5. Singer M, Deutschman CS, Seymour CW, ShankarHari M, Annane D et al. The third international consensus definitions for sepsis and septic shock. JAMA 2016
  6. doi: 10.1001 / JAMA.2016.0287 6. Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD et al. Assessment of clinical criteria for sepsis: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016
  7. doi: 10.1001 / JAMA.2016.0288 7. Sakr Y, Ferrer R, Reinhart K, Beale R, Rhodes A et al. The intensive care global study on severe acute respiratory infection (IC-GLOSSARI): a multicenter, multinational, 14-day inception cohort study. Intensive Care Medicine 2016
  8. 42 (5): 817-828. doi: 10.1007 / s00134-015-4206-2 8. Zhang C, Zhu N, Xie Z, Lu R, He B et al. Viral etiology and clinical profiles of children with severe acute respiratory infections in China. PloS One 2013
  9. e72606. doi.org/10.1371/ journal.pone.0072606 9. Singleton RJ, Bulkow LR, Miernyk K, DeByle C, Pruitt L et al. Viral respiratory infections in hospitalized and community control children in Alaska. Journal of Medical Virology 2010
  10. 82 (7): 1282-1290. doi.org/10.1002/jmv.21790 10. Al-Abdallat M, Dawson P, Haddadin AJ, El-Shoubary W, Dueger E et al. Influenza hospitalization epidemiology from a severe acute respiratory infection surveillance system in Jordan, January 2008-February 2014. Influenza and Other Respiratory Viruses 2016
  11. 10 (2): 91-97. doi.org/10.1111/irv.12354 11. Feikin DR, Njenga MK, Bigogo G, Aura B, Aol G et al. Viral and bacterial causes of severe acute respiratory illness among c