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Journals / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 6

Assessment of the visual pathways in patients with neurofibromatosis-1 by 3S-space technique with 3-Tesla MRI

Ali VARAN
Banu ANLAR
Tülay KANSU
Mehmet BEYAZAL
Özge SARAÇ
Oktay ALGIN
Pages
1626–1633
Publication Date
2022-11-04
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

High-resolution craniumimaging with the 3D-SPACE technique using 3T-MRI seems to be helpful for detection of the optic pathway morphology and pathologiesin NF-1 patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: We aimed to evaluate the size/tortuosity of the optic nerve (ON) and the dilatation of the ON sheath (ONS) inneurofibromatosis type 1 (NF-1) patients with 3T-MRI, and to assess the usefulness of 3D-SPACE in imaging the optic pathway, ON,and ONS in NF-1 patients.Materials and methods: Twenty consecutive NF-1 patients without optic pathway glioma (OPG) (Group 1), 16 consecutive NF-1patients with OPG (Group 2), and 19 controls were included in this study.
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Key Findings & Data:The thickness and tortuosity of the ON and the diameter ofthe ONS were measured on STIR and 3D-SPACE images.Results: The thickness of the ON was similar in all groups on STIR images (P>0.05).
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Conclusion & Impact:High-resolution craniumimaging with the 3D-SPACE technique using 3T-MRI seems to be helpful for detection of the optic pathway morphology and pathologiesin NF-1 patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: We aimed to evaluate the size/tortuosity of the optic nerve (ON) and the dilatation of the ON sheath (ONS) inneurofibromatosis type 1 (NF-1) patients with 3T-MRI, and to assess the usefulness of 3D-SPACE in imaging the optic pathway, ON,and ONS in NF-1 patients.Materials and methods: Twenty consecutive NF-1 patients without optic pathway glioma (OPG) (Group 1), 16 consecutive NF-1patients with OPG (Group 2), and 19 controls were included in this study. The thickness and tortuosity of the ON and the diameter ofthe ONS were measured on STIR and 3D-SPACE images.Results: The thickness of the ON was similar in all groups on STIR images (P>0.05). The mean ONS diameter was higher in Group 2with this sequence (P=0.009). Controls had significantly lower grades of ON tortuosity than Groups 1 and 2 (P=0.001), and Group 1 hadsignificantly lower ON tortuosity compared to Group 2 (P=0.001). Severe tortuosity was only detected in Group 2.Conclusion: ON tortuosity and ONS diameter were increased in NF-1 patients in the presence of OPG. High-resolution craniumimaging with the 3D-SPACE technique using 3T-MRI seems to be helpful for detection of the optic pathway morphology and pathologiesin NF-1 patients.

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Cite This Article

VARAN, A., ANLAR, B., KANSU, T., BEYAZAL, M., SARAÇ, Ö., ALGIN, O. (2022). Assessment of the visual pathways in patients with neurofibromatosis-1 by 3S-space technique with 3-Tesla MRI. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 6, 1626–1633. https://ajindex.com/articles/609979

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