SavedAdd your journal

Journals / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 6

Evaluation of medial olivocochlear efferent system and hearing loss in patients with primary Sjögren’s syndrome

Zafer GÜNENDİ
Recep KARAMERT
Emre ORHAN
Serdar Can GÜVEN
Bülent GÜNDÜZ
Nuriye YILDIRIM
Pages
1647–1654
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, there is a need for more tests, including auditory brainstem response, to evaluate the afferentauditory system in pSS.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Autoimmune diseases are a remarkable issue for researchers due to their adverse effects on the auditory system, butfor primary Sjögren’s syndrome (pSS) there is little research on the comprehensive audiological findings in literature.
📊
Key Findings & Data:The main objectiveof this study was to investigate the medial olivocochlear efferent functions of subjects with pSS and to examine the audiological findings.Materials and methods: The study included 36 subjects with pSS and 36 healthy subjects.
💡
Conclusion & Impact:However, there is a need for more tests, including auditory brainstem response, to evaluate the afferentauditory system in pSS.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: Autoimmune diseases are a remarkable issue for researchers due to their adverse effects on the auditory system, butfor primary Sjögren’s syndrome (pSS) there is little research on the comprehensive audiological findings in literature. The main objectiveof this study was to investigate the medial olivocochlear efferent functions of subjects with pSS and to examine the audiological findings.Materials and methods: The study included 36 subjects with pSS and 36 healthy subjects. All the subjects underwent testing includingpure tone, speech, and high frequency audiometry; tympanometry and acoustic reflexes; distortion product otoacoustic emissions(DPOAE); and suppression of DPOAE.Results: The hearing thresholds of the pSS group were higher than those of the control at all frequencies (P 0.05).Conclusion: The study indicates that because of obtaining normal suppression levels in DPOAE, the medial olivocochlear efferentsystem is functional in pSS. However, there is a need for more tests, including auditory brainstem response, to evaluate the afferentauditory system in pSS.

🔖

Cite This Article

GÜNENDİ, Z., KARAMERT, R., ORHAN, E., GÜVEN, S. C., GÜNDÜZ, B., YILDIRIM, N. (2022). Evaluation of medial olivocochlear efferent system and hearing loss in patients with primary Sjögren’s syndrome. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 6, 1647–1654. https://ajindex.com/articles/609914

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (4)

  1. Ferro F, Vagelli R, Bruni C, Cafaro G, Marcucci E et al. One year in review 2016: Sjögren’s syndrome. Clinical Experimental Rheumatology 2016; 34 (2): 161-171
  2. Maciel G, Crowson CS, Matteson EL, Cornec D. Prevalence of primary Sjögren’s syndrome in a US population‐based cohort. Arthritis Care and Research 2017; 69 (10): 1612-1616. doi: 10.1002/acr.23173 3. Patel R, Shahane A. The epidemiology of Sjögren’s syndrome. Clinical Epidemiology 2014; 30 (6): 247-255. doi: 10.2147/CLEP. S47399 4. Birlik M, Akar S, Gurler O, Sari I, Birlik B et al. Prevalence of primary Sjogren’s syndrome in Turkey: a population‐based epidemiological study. International Journal of Clinical Practice 2009; 63 (6): 954-961. doi:10.1111/j.1742-1241.2008.01749.x 5. Eckhard A, Gleiser C, Arnold H, Rask-Andersen H, Kumagami H et al. Water channel proteins in the inner ear and their link to hearing impairment and deafness. Molecular Aspects of Medicine 2012; 33 (5-6): 612-637. doi:10.1016/j.mam.2012.06.004 6. González JLT, Torres JR, Ríos YH, González MJV, MendezSaenz MA et al. Extended high-frequency audiometry as early detection of hearing loss in primary Sjögren syndrome. Clinical Rheumatology 2017; 36 (10): 2237-2241. doi: 10.1007/s10067- 017-3750-2 7. Thanooja CV, Augustine AM, Lepcha A, Sandhya P, Tyagi AK et al. Audiological profile in primary Sjögren’s syndrome in a tertiary care setting and its clinical implications. Indian Journal of Otolaryngology Head and Neck Surgery 2018; 70 (1): 59-65. doi:10.1007/s12070-015-0956-y 8. Thanooja CV, Augustine AM, Lepcha A, Sandhya P, Tyagi AK et al. Early hearing loss detection in rheumatoid arthritis and primary Sjögren syndrome using extended high frequency audiometry. Clinical Rheumatology 2018; 37 (2): 367-373. doi:10.1007/s10067-017-3959-0 9. Oztürk A, Yalçin Ş, Kaygusuz I, Sahin S, Gök U et al. Highfrequency hearing loss and middle ear involvement in rheumatoid arthritis. American Journal of Otolaryngology 2004; 25 (6): 411-417. doi: 10.1016/j.amjoto.2004.06.001 10. Kemp DT. Otoacoustic emissions, their origin in cochlear function, and use. British Medical Bulletin 2002; 63: 223-241
  3. Maison S, Micheyl C, Collet L. The medial olivocochlear efferent system in humans: structure and function. Scandinavian Audiology Supplementum 1999; 51: 77-84
  4. Hatzopoulos S, Amoroso C, Aimoni C, Monaco AL, Govoni M et al. hearing loss evaluation of Sjogren’s Syndrome using distortion product otoacoustic emissions. Acta Oto-Laryngologica 2002;