Journals / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 1

Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience

Pages
222–229
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

More interventions are warranted to boost the quality oflife in aging PLWHA.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: The HIV-infected population is aging, and the concomitant comorbidities increase the likelihood of polypharmacy.There is a scarcity of data for determining drug-related problems in people living with HIV/AIDS (PLWHA).Materials and methods: This cross-sectional study was carried out between 1 September 2015 and 1 July 2016.
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Key Findings & Data:PCNE Classification V 7.0 was used classify incident drug-related problems (DRPs).Results: The mean age of the patients was 40.4 ± 13.06 years.
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Conclusion & Impact:More interventions are warranted to boost the quality oflife in aging PLWHA.
🔬Design:Modeling & Simulation
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Background/aim: The HIV-infected population is aging, and the concomitant comorbidities increase the likelihood of polypharmacy.There is a scarcity of data for determining drug-related problems in people living with HIV/AIDS (PLWHA).Materials and methods: This cross-sectional study was carried out between 1 September 2015 and 1 July 2016. All patients underwenta face-to-face interview with a clinical pharmacist. PCNE Classification V 7.0 was used classify incident drug-related problems (DRPs).Results: The mean age of the patients was 40.4 ± 13.06 years. The rate of polypharmacy was 66.1% in patients with comorbidities and12.3% in those without comorbidities (P 3 ART drugs was associated with more DRPs in the logistic regression model (odds ratio: 8.299, 95% confidence interval:1.924–35.803). Fifty-eight interventions were performed in 45 (24.9%) patients. Clinical pharmacist interventions were performed in18.9% of patients without polypharmacy and in 38.9% of patients with polypharmacy (P < 0.001).Conclusion: DRPs and polypharmacy are common among elderly PLWHA. More interventions are warranted to boost the quality oflife in aging PLWHA.

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Cite This Article

DEMİRKAN, K., İNKAYA, A. Ç., KARA, E., HAKLI, D. A., ÜNAL, S. (2022). Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 1, 222–229. https://ajindex.com/articles/609864

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