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Journals / Turkish Journal of Medical Sciences / 2020 / Cilt: 50 - Sayı: 2

25-Hydroxy vitamin D level is associated with sleep disturbances in patients with chronic kidney disease on hemodialysis: a cross-sectional study

Demet YAVUZ
Düriye Sıla KARAGÖZ ÖZEN
Zeynep Banu RAMAZANOĞLU
Mehmet Derya DEMİRAĞ
Rahman YAVUZ
Pages
298–303
Publication Date
2022-11-05
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Vitamin D levelswere measured for 121 patients, and statistical analysis was done by using SPSS.Results: Regression analyses demonstrated that low levels of 25(OH)D and high BDI score were independent risk factors for poor sleepquality [ORs were 0.668 (0.566–0.789), 1.080 (1.001–1.164), and 1.080 (1.001–1.164), respectively].Conclusion: Our results suggest that deficiency of 25(OH)D is an important independent risk factor for poor sleep quality inhemodialysis patients.

📌 3 Key Takeaways

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Objective & Hypothesis:aim of this study is to determine the relationship between vitamin D deficiency and depression status and sleep disorders of patients ondialysis.Materials and methods: In this cross-sectional study, 121 hemodialysis patients were enrolled.
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Key Findings & Data:All patients had been on hemodialysisfor at least six months at the time of the study.
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Conclusion & Impact:Vitamin D levelswere measured for 121 patients, and statistical analysis was done by using SPSS.Results: Regression analyses demonstrated that low levels of 25(OH)D and high BDI score were independent risk factors for poor sleepquality [ORs were 0.668 (0.566–0.789), 1.080 (1.001–1.164), and 1.080 (1.001–1.164), respectively].Conclusion: Our results suggest that deficiency of 25(OH)D is an important independent risk factor for poor sleep quality inhemodialysis patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

aim of this study is to determine the relationship between vitamin D deficiency and depression status and sleep disorders of patients ondialysis.Materials and methods: In this cross-sectional study, 121 hemodialysis patients were enrolled. All patients had been on hemodialysisfor at least six months at the time of the study. Sleep quality and depression status were measured by using specific inventories. All thepatients filled out Pittsburg Sleep Quality Index (PSQI) and Beck Depression Inventory (BDI), and gave blood samples. Vitamin D levelswere measured for 121 patients, and statistical analysis was done by using SPSS.Results: Regression analyses demonstrated that low levels of 25(OH)D and high BDI score were independent risk factors for poor sleepquality [ORs were 0.668 (0.566–0.789), 1.080 (1.001–1.164), and 1.080 (1.001–1.164), respectively].Conclusion: Our results suggest that deficiency of 25(OH)D is an important independent risk factor for poor sleep quality inhemodialysis patients.

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Cite This Article

YAVUZ, D., ÖZEN, D. S. K., RAMAZANOĞLU, Z. B., DEMİRAĞ, M. D., YAVUZ, R. (2022). 25-Hydroxy vitamin D level is associated with sleep disturbances in patients with chronic kidney disease on hemodialysis: a cross-sectional study. Turkish Journal of Medical Sciences, Cilt: 50 - Sayı: 2, 298–303. https://ajindex.com/articles/609817

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References (14)

  1. Wintermeyer E, Ihle C, Ehnert S, Stöckle U, Ochs G et al. Crucial role of vitamin D in the musculoskeletal system. Nutrients 2016; 8 (6): E319
  2. Musiol IM, Stumpf WE, Bidmon HJ, Heiss C, Mayerhofer A et al. Vitamin D nuclear binding to neurons of the septal, substriatal and amygdaloid area in the Siberian hamster (Phodopus sungorus) brain. Neuroscience 1992; 48 (4): 841- 848
  3. Stumpf WE, O’Brien LP. 1,25(OH)2 vitamin D3 sites of action in the brain. An autoradiographic study. Histochemistry 1987; 87 (5): 393-406
  4. Yeşil Y, Kuyumcu ME, Kara Ö, Halaçlı B, Etgul S et al. Vitamin D status and its association with gradual decline in cognitive function. Turkish Journal of Medical Sciences 2015; 45 (5): 1051-1057
  5. González EA, Sachdeva A, Oliver DA, Martin KJ. Vitamin D insufficiency and deficiency in chronic kidney disease. A single center observational study. American Journal of Nephrology 2004; 24 (5): 503-510
  6. Nigwekar SU, Bhan I, Thadhani R. Ergocalciferol and cholecalciferol in CKD. American Journal of Kidney Diseases 2012; 60 (1): 139-156
  7. Chen WC, Lim PS, Wu WC, Chiu HC, Chen CH et al. Sleep behavior disorders in a large cohort of Chinese (Taiwanese) patients maintained by long-term hemodialysis. American Journal of Kidney Diseases 2006; 48 (2): 277-284
  8. Merlino G, Gigli GL, Valente M. Sleep disturbances in dialysis patients. Journal of Nephrology 2008; 21 (Suppl. 13): S66-70
  9. Iliescu EA, Coo H, McMurray MH, Meers CL, Quinn MM et al. Quality of sleep and health-related quality of life in haemodialysis patients. Nephrology Dialysis Transplantation 2003; 18 (1): 126-132
  10. Chonchol M, Greene T, Zhang Y, Hoofnagle AN, Cheung AK. Low vitamin D and high fibroblast growth factor 23 serum levels associate with infectious and cardiac deaths in the HEMO Study. Journal of American Society Nephrology 2016; 27 (1): 227-237
  11. Iseki K, Tsuruya K, Kanda E, Nomura T, Hirakata H. Effects of sleepiness on survival in Japanese hemodialysis patients: J-DOPPS study. Nephron Clinical Practice 2014; 128 (3-4): 333-340
  12. Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Research 1989; 28: 193-213
  13. Ağargün YM, Kara H, Anlar Ö. Validity and reliability of Pittsburgh Sleep Quality Index. Türk Psikiyatri Dergisi 1996; 7 (2): 107-111
  14. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Archives of