SavedAdd your journal

Journals / Turkish Journal of Medical Sciences / 2021 / Cilt: 51 - Sayı: 6

Prognostic factors for 30-days mortality in eighty years aged and older critically ill patients: a single center retrospective cohort study

Umut Sabri KASAPOĞLU
Osman KAÇMAZ
Abdullah GÖK
Merih YILDIZ EGLEN
Hasan ŞAYAN
Fatih ÇOLAK
Pages
2968–2977
Publication Date
2022-11-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

And, the median age of the patients was 85 (80–106) years. 30-days and overall ICU mortality rates were found 30.1% and 34.6%, respectively.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Nowadays, with the rise in average life expectancy, the rate of hospitalization of the older population in intensive care unit (ICU) is gradually increasing.
📊
Key Findings & Data:Materials and methods: This retrospective cohort study was performed between January 2019 and February 2020.
💡
Conclusion & Impact:And, the median age of the patients was 85 (80–106) years. 30-days and overall ICU mortality rates were found 30.1% and 34.6%, respectively.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Background/aim: Nowadays, with the rise in average life expectancy, the rate of hospitalization of the older population in intensive care unit (ICU) is gradually increasing. Unfortunately, there are no ideal combination of prognostic factors predicting the mortality in older patients admitted to the ICU. In the present study, we aim to determine the prognostic factors and their impacts on short-time mortality in older critically ill patients. Materials and methods: This retrospective cohort study was performed between January 2019 and February 2020. We included 133 patients aged ≥80 years and hospitalized ≥24 h in the ICU. Results: A total of 133 critically ill patients enrolled in the present study. And, the median age of the patients was 85 (80–106) years. 30-days and overall ICU mortality rates were found 30.1% and 34.6%, respectively. The patients were grouped as survivors (n = 94) and nonsurvivors (n = 39). Hospital length of stay before the ICU admission was found significantly longer in nonsurvivors (p = 0.001). Sequential organ failure assessment (SOFA) score and acute physiology and chronic health evaluation-II (APACHE-II) score were significantly higher in nonsurvivors (p < 0.001, p < 0.001). Also, blood lactate level and glucose level were respectively significantly higher in nonsurvivors (p < 0.001, p = 0.006). We found that modified nutrition risk in critically ill (mNUTRIC) score and prehospital clinical frailty scale (CFS) were independent prognostic factors for the older critically ill patients (HR = 9.19, 95% CI=1.47–57.32, p = 0.018, HR = 20.16, 95% CI = 2.63–54.07, p =0.004). Conclusion: mNUTRIC score and prehospital CFS score were the most important prognostic factors in the admission of older patients to intensive care units.Key words: Older, ICU, frailty, modified NUTRIC score, prognostic factors, mortality

🔖

Cite This Article

KASAPOĞLU, U. S., KAÇMAZ, O., GÖK, A., EGLEN, M. Y., ŞAYAN, H., ÇOLAK, F. (2022). Prognostic factors for 30-days mortality in eighty years aged and older critically ill patients: a single center retrospective cohort study. Turkish Journal of Medical Sciences, Cilt: 51 - Sayı: 6, 2968–2977. https://ajindex.com/articles/609780

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Sim YS, Jung H, Shin TR, Kim DG, Park SM. Mortality and outcomes in very elderly patients 90 years of age or older admitted to the ICU. Respiratory Care. 2015
  2. 60 (3): 347-355. doi: 10.4187/respcare.03155 2. Robert R, Skrifvars MB, Ranzani OT. Is this critically ill patient elderly or too old? Intensive Care Medicine. 2017
  3. 43 (12): 1884-1886. doi: 10.1007/s00134-017-4965-z 3. Bagshaw SM, Webb SA, Delaney A, George C, Pilcher D et al. Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis. Critical Care. 2009
  4. 13 (2): R45. doi: 10.1186/cc7768 4. Flaatten H, De Lange DW, Morandi A, Andersen FH, Artigas A et al. The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years). Intensive Care Medicine. 2017
  5. 43 (12): 1820-1828. doi: 10.1007/s00134- 017-4940-8 5. Heyland D, Cook D, Bagshaw SM, Garland A, Stelfox HT et al. The very elderly admitted to ICU: A quality finish? Critical Care Medicine. 2015
  6. 43 (7): 1352-1360. doi: 10.1097/ CCM.0000000000001024 6. Flaatten H, de Lange DW, Artigas A, Bin D, Moreno R et al. The status of intensive care medicine research and a future agenda for very old patients in the ICU. Intensive Care Medicine. 2017
  7. 43 (9): 1319-1328. doi: 10.1007/s00134-017-4718-z 7. Nates JL, Nunnally M, Kleinpell R, Blosser S, Goldner J et al. ICU admission, discharge, and triage guidelines: a framework to enhance clinical operations, development of institutional policies, and further research. Critical Care Medicine. 2016
  8. 44 (8): 1553-1602. doi: 10.1097/CCM.0000000000001856. 8. Fronczek J, Polok KJ, Nowak-Kozka I, Wludarczyk A, Gorka J et al. Frailty is associated with an increased mortality among patients ≥ 80 years old treated in Polish ICUs. Anaesthesiology Intensive Therapy. 2018
  9. 50 (4): 245-251. doi: 10.5603/ait. a2018.0032 9. Rahman A, Hasan RM, Agarwala R, Martin C, Day AG et al. Identifying critically-ill patients who will benefit most from nutritional therapy: further validation of the “modified NUTRIC” nutritional risk assessment tool. Clinical Nutrition. 2016
  10. 35 (1): 158-162. doi: 10.1016/j.clnu.2015.01.015 10. Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB et al. A global clinical measure of fitness and frailty in elderly people. Canadian Medical Association Journal. 2005
  11. 173 (5): 489-495. doi: 10.1503/cmaj.050051 11. Campbell NN, Tooley MA, Willatts SM. APACHE II scoring system on a general intensive care unit: audit of dai